Animal models of depression: what can they teach us about the human disease?
Depression is apparently the most common psychiatric disease among the mood disorders
affecting about 10% of the adult population. The etiology and pathogenesis of depression …
affecting about 10% of the adult population. The etiology and pathogenesis of depression …
The recent progress in animal models of depression
Q Wang, MA Timberlake II, K Prall, Y Dwivedi - Progress in Neuro …, 2017 - Elsevier
Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …
and mortality. Despite the growing number of studies that have emerged, the precise …
Animal models and human depressive disorders
RJ Katz - Neuroscience & Biobehavioral Reviews, 1981 - Elsevier
Clinical depressive disorders are complex in presentation, dissimilar in origins and course,
and often pleomorphic in character. An adequate understanding of their origins, biological …
and often pleomorphic in character. An adequate understanding of their origins, biological …
Animal models of depression: are there any?
MF O'Neil, NA Moore - Human Psychopharmacology: Clinical …, 2003 - Wiley Online Library
Simple tests for antidepressant‐like activity, such as 5‐HTP‐induced syndrome or reserpine‐
induced hypomotility, are often mechanism‐based tests, pharmacologically specific for …
induced hypomotility, are often mechanism‐based tests, pharmacologically specific for …
Animal models of depression
P Willner - Handbook of depression and anxiety. A biological …, 1991 - cell.com
Animal models of depression are dence between drug actions in the most hrquently
encountered model and in the clinic), face within the pharmaceutical in- validity …
encountered model and in the clinic), face within the pharmaceutical in- validity …
Animal models of depression: pros and cons
J Harro - Cell and tissue research, 2019 - Springer
Animal models of depression are certainly needed but the question in the title has been
raised owing to the controversies in the interpretation of the readout in a number of tests, to …
raised owing to the controversies in the interpretation of the readout in a number of tests, to …
Animal models as simulations of depression
P Willner - Trends in pharmacological sciences, 1991 - Elsevier
The most familiar usage of animal models of depression is as antidepressant screening tests
Paul Willner reviews their usage in a different context—as simulations of depression. The …
Paul Willner reviews their usage in a different context—as simulations of depression. The …
Genetic rodent models of depression
M El Yacoubi, JM Vaugeois - Current opinion in pharmacology, 2007 - Elsevier
Are there appropiate rodent models for human depressive disorders? A model that targets a
core aspect of depression can become a helpful tool in the analysis of the causes, genetic or …
core aspect of depression can become a helpful tool in the analysis of the causes, genetic or …
Animal models of major depression and their clinical implications
Major depressive disorder is a common, complex, and potentially life-threatening mental
disorder that imposes a severe social and economic burden worldwide. Over the years …
disorder that imposes a severe social and economic burden worldwide. Over the years …
[PDF][PDF] Behavioral animal models of depression
Y Hua-Cheng, CAO Xiong, D Manas, Z Xin-Hong… - Neurosci …, 2010 - researchgate.net
Depression is a chronic, recurring and potentially life-threatening illness that affects up to
20% of the population across the world. Despite its prevalence and considerable impact on …
20% of the population across the world. Despite its prevalence and considerable impact on …