A network pharmacology approach to predict potential targets and mechanisms of “Ramulus Cinnamomi (cassiae) – Paeonia lactiflora” herb pair in the treatment of …

HT Pan, ZQ Xi, XQ Wei, K Wang - Annals of Medicine, 2022 - Taylor & Francis
Abstract Background Traditional Chinese medicine (TCM) prescriptions have multiple
bioactive properties.“Gui Zhi–Shao Yao” herb pair is widely used to treat chronic pain (CP) …

Identification of potential biomarkers of depression and network pharmacology approach to investigate the mechanism of key genes and therapeutic traditional …

Y Shi, D Chen, S Ma, H Xu… - … Based Complementary and …, 2021 - Wiley Online Library
Background. To explore the potential target of depression and the mechanism of related
traditional Chinese medicine in the treatment of depression. Method. Differential gene …

Reveals of new candidate active components in hemerocallis radix and its anti-depression action of mechanism based on network pharmacology approach

HY Lin, JC Tsai, LY Wu, WH Peng - International journal of molecular …, 2020 - mdpi.com
The global depression population is showing a significant increase. Hemerocallis fulva L. is
a common Traditional Chinese Medicine (TCM). Its flower buds are known to have ability to …

Integrated network pharmacology and metabolomics to dissect the combination mechanisms of Bupleurum chinense DC-Paeonia lactiflora Pall herb pair for treating …

X Li, XM Qin, JS Tian, XX Gao, GH Du… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance The compatibility of Bupleurum chinense DC (Chaihu)-
Paeonia lactiflora Pall (Baishao) is one of the most accepted herb pairs in traditional …

Mode of Action of Shan‐Zhu‐Yu (Cornus officinalis Sieb. et Zucc.) in the Treatment of Depression Based on Network Pharmacology

P Liu, P Yang, L Zhang - Evidence‐Based Complementary and …, 2020 - Wiley Online Library
Background. Although the traditional Chinese medicine Shan‐Zhu‐Yu may be efficacious
against depression, its mechanism of action is unknown. In this study, we aimed to explore …

An Investigation of the Molecular Mechanisms Underlying the Analgesic Effect of Jakyak‐Gamcho Decoction: A Network Pharmacology Study

HS Lee, IH Lee, K Kang, SI Park… - Evidence‐Based …, 2020 - Wiley Online Library
Herbal drugs have drawn substantial interest as effective analgesic agents; however, their
therapeutic mechanisms remain to be fully understood. To address this question, we …

The synergistic anti-depression effects of different efficacy groups of Xiaoyaosan as demonstrated by the integration of network pharmacology and serum …

X Liu, Y Wang, F Wei, M Lv, P Qu, S Chen, S Li… - … of Pharmaceutical and …, 2021 - Elsevier
Compatibility investigations are vital but also the most difficult aspect of traditional Chinese
medicine (TCM) prescriptions. Previous researches have demonstrated that Xiaoyaosan …

A network pharmacology study on analgesic mechanism of Yuanhu-Baizhi herb pair

B Mi, Q Li, T Li, J Marshall, J Sai - BMC Complementary Medicine and …, 2020 - Springer
Background Millions of people are suffering from chronic pain conditions, such as
headache, arthritis, cancer. Apart from western medicines, traditional Chinese medicines are …

Action mechanism of Roman chamomile in the treatment of anxiety disorder based on network pharmacology

Y Jia, J Zou, Y Wang, X Zhang, Y Shi… - Journal of food …, 2021 - Wiley Online Library
Anxiety disorder is a common psychiatric disease. Roman chamomile as medicine or tea
has long been used as a mild tranquilizer to reduce anxiety, but the mechanism is unclear …

A network pharmacology approach to determine the synergetic mechanisms of herb couple for treating rheumatic arthritis

X Xu, J Bi, L Ping, P Li, F Li - Drug Design, Development and …, 2018 - Taylor & Francis
Purpose The purpose of this study was to investigate the therapeutic mechanism (s) of
Clematis chinensis Osbeck/Notopterygium incisum KC Ting ex HT (CN). Methods A network …