[HTML][HTML] Immunotherapy in colorectal cancer: rationale, challenges and potential

K Ganesh, ZK Stadler, A Cercek… - Nature reviews …, 2019 - nature.com
Following initial successes in melanoma treatment, immunotherapy has rapidly become
established as a major treatment modality for multiple types of solid cancers, including a …

Expanding the scope of immunotherapy in colorectal cancer: current clinical approaches and future directions

M Kreidieh, D Mukherji, S Temraz… - BioMed research …, 2020 - Wiley Online Library
The success of immune checkpoint inhibitors (ICIs) in an increasing range of heavily
mutated tumor types such as melanoma has culminated in their exploration in different …

Immunotherapy in colorectal cancer: current and future strategies

A Ooki, E Shinozaki, K Yamaguchi - Journal of the Anus, Rectum and …, 2021 - jstage.jst.go.jp
Despite the recent advances in the systemic treatment of metastatic colorectal cancer
(mCRC), prognostic outcomes have remained to be poor. Thus, what is needed is an …

Immunotherapy with immune checkpoint inhibitors in colorectal cancer: what is the future beyond deficient mismatch-repair tumours?

N Huyghe, P Baldin… - Gastroenterology report, 2020 - academic.oup.com
Following initial success in melanoma and lung tumours, immune checkpoint inhibitors
(ICIs) are now well recognized as a major immunotherapy treatment modality for multiple …

[HTML][HTML] Immunotherapy in colorectal cancer: current achievements and future perspective

A Fan, B Wang, X Wang, Y Nie, D Fan… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Following dramatic success in many types of advanced solid tumors, interest in
immunotherapy for the treatment of colorectal cancer (CRC) is increasingly growing. Given …

[HTML][HTML] Immunotherapy: recent advances and its future as a neoadjuvant, adjuvant, and primary treatment in colorectal cancer

I Yu, A Dakwar, K Takabe - Cells, 2023 - mdpi.com
Immunotherapy in colorectal cancer (CRC) has made great strides within the past decade.
Immune checkpoint inhibitors are a class of immunotherapy and have been shown to greatly …

Latest evidence on immune checkpoint inhibitors in metastatic colorectal cancer: A 2022 update

AE Boukouris, M Theochari, D Stefanou… - Critical reviews in …, 2022 - Elsevier
The long-term remissions induced by immune-checkpoint inhibitors (ICIs) in many types of
cancers have opened up the possibility of a broader use of immunotherapy in less …

Immunotherapy for colorectal cancer: a review of current and novel therapeutic approaches

AJ Franke, WP Skelton IV, JS Starr… - JNCI: Journal of the …, 2019 - academic.oup.com
Colorectal cancer (CRC) remains a leading cause of cancer-related deaths in the United
States. Although immunotherapy has dramatically changed the landscape of treatment for …

[HTML][HTML] Immunotherapy for colorectal cancer

PM Boland, WW Ma - Cancers, 2017 - mdpi.com
The recent success of anti-PD1 drugs in metastatic colorectal cancer patients with mismatch
repair deficiency generated overwhelming enthusiasm for immunotherapy in the disease …

Perspectives on treatment of metastatic colorectal cancer with immune checkpoint inhibitor therapy

MA Morse, H Hochster, A Benson - The oncologist, 2020 - academic.oup.com
Despite lengthening survival, death rates from metastatic colorectal cancer (CRC) remain
unacceptably high, with a bright spot being the demonstration of durable responses in …