[HTML][HTML] Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities

LJ Cocka, P Bates - 2012 - journals.plos.org
Tetherin (BST-2/CD317/HM1. 24) is an IFN induced transmembrane protein that restricts
release of a broad range of enveloped viruses. Important features required for Tetherin …

[HTML][HTML] Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants

MW McNatt, T Zang, T Hatziioannou, M Bartlett… - PLoS …, 2009 - journals.plos.org
Tetherin/BST-2/CD317 is a recently identified antiviral protein that blocks the release of
nascent retrovirus, and other virus, particles from infected cells. An HIV-1 accessory protein …

Structural insight into the mechanisms of enveloped virus tethering by tetherin

H Yang, J Wang, X Jia, MW McNatt… - Proceedings of the …, 2010 - National Acad Sciences
Tetherin/BST2 is a type-II membrane protein that inhibits the release of a range of enveloped
viruses, including HIV-1. Here we report three crystal structures of human tetherin, including …

[HTML][HTML] Vpu binds directly to tetherin and displaces it from nascent virions

MW McNatt, T Zang, PD Bieniasz - PLoS pathogens, 2013 - journals.plos.org
Tetherin (Bst2/CD317/HM1. 24) is an interferon-induced antiviral host protein that inhibits
the release of many enveloped viruses by tethering virions to the cell surface. The HIV-1 …

[HTML][HTML] Tetherin inhibits HIV-1 release by directly tethering virions to cells

D Perez-Caballero, T Zang, A Ebrahimi, MW McNatt… - Cell, 2009 - cell.com
Tetherin is an interferon-induced protein whose expression blocks the release of HIV-1 and
other enveloped viral particles. The underlying mechanism by which tetherin functions and …

Identification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility

T Kobayashi, H Ode, T Yoshida, K Sato, P Gee… - Journal of …, 2011 - Am Soc Microbiol
Tetherin, also known as BST-2/CD317/HM1. 24, is an antiviral cellular protein that inhibits
the release of HIV-1 particles from infected cells. HIV-1 viral protein U (Vpu) is a specific …

Feline tetherin is characterized by a short N-terminal region and is counteracted by the feline immunodeficiency virus envelope glycoprotein

M Celestino, A Calistri, C Del Vecchio, C Salata… - Journal of …, 2012 - Am Soc Microbiol
Tetherin (BST2) is the host cell factor that blocks the particle release of some enveloped
viruses. Two putative feline tetherin proteins differing at the level of the N-terminal coding …

Antiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteraction

A Le Tortorec, S Willey, SJD Neil - Viruses, 2011 - mdpi.com
Tetherin (BST2/CD317) has been recently recognized as a potent interferon-induced
antiviral molecule that inhibits the release of diverse mammalian enveloped virus particles …

Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein

A Le Tortorec, SJD Neil - Journal of virology, 2009 - Am Soc Microbiol
ABSTRACT Tetherin (CD317/BST-2), an interferon-induced membrane protein, restricts the
release of nascent retroviral particles from infected cell surfaces. While human …

[HTML][HTML] Immunoelectron microscopic evidence for Tetherin/BST2 as the physical bridge between HIV-1 virions and the plasma membrane

J Hammonds, JJ Wang, H Yi, P Spearman - PLoS pathogens, 2010 - journals.plos.org
Tetherin/BST2 was identified in 2008 as the cellular factor responsible for restricting HIV-1
replication at a very late stage in the lifecycle. Tetherin acts to retain virion particles on the …