Riboflavin transport and metabolism in humans

M Barile, TA Giancaspero, P Leone, M Galluccio… - Journal of inherited …, 2016 - Springer
Recent studies elucidated how riboflavin transporters and FAD forming enzymes work in
humans and create a coordinated flavin network ensuring the maintenance of cellular …

Disorders of riboflavin metabolism

S Balasubramaniam, J Christodoulou… - Journal of inherited …, 2019 - Wiley Online Library
Abstract Riboflavin (vitamin B2), a water‐soluble vitamin, is an essential nutrient in higher
organisms as it is not endogenously synthesised, with requirements being met principally by …

Biosynthesis of flavin cofactors in man: implications in health and disease

M Barile, T Anna Giancaspero, C Brizio… - Current …, 2013 - ingentaconnect.com
The primary role of the water-soluble vitamin B2, ie riboflavin, in cell biology is connected
with its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases …

[PDF][PDF] Riboflavin metabolism: role in mitochondrial function

S Balasubramaniam, J Yaplito-Lee - J. Transl. Genet. Genom, 2020 - f.oaes.cc
Riboflavin, known as vitamin B2, a water-soluble vitamin, is an essential nutrient in
vertebrates, hence adequate dietary intake is imperative. Riboflavin plays a role in a variety …

An update on the genetics, clinical presentation, and pathomechanisms of human riboflavin transporter deficiency

B O'Callaghan, AM Bosch… - Journal of Inherited …, 2019 - Wiley Online Library
Riboflavin transporter deficiency (RTD) is a rare neurological condition that encompasses
the Brown‐Vialetto‐Van Laere and Fazio‐Londe syndromes since the discovery of …

[PDF][PDF] Riboflavin-responsive and-non-responsive mutations in FAD synthase cause multiple acyl-CoA dehydrogenase and combined respiratory-chain deficiency

RKJ Olsen, E Koňaříková, TA Giancaspero… - The American journal of …, 2016 - cell.com
Multiple acyl-CoA dehydrogenase deficiencies (MADDs) are a heterogeneous group of
metabolic disorders with combined respiratory-chain deficiency and a neuromuscular …

[HTML][HTML] Remaining challenges in cellular flavin cofactor homeostasis and flavoprotein biogenesis

TA Giancaspero, M Colella, C Brizio, G Difonzo… - Frontiers in …, 2015 - frontiersin.org
The primary role of the water-soluble vitamin B2 (riboflavin) in cell biology is connected with
its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases …

Mitochondrial localization of human FAD synthetase isoform 1

EM Torchetti, C Brizio, M Colella, M Galluccio… - Mitochondrion, 2010 - Elsevier
FAD synthetase or ATP: FMN adenylyl transferase (FADS or FMNAT, EC 2.7. 7.2) is a key
enzyme in the metabolic pathway that converts riboflavin into the redox cofactor FAD. We …

Emerging roles for riboflavin in functional rescue of mitochondrial β-oxidation flavoenzymes

BJ Henriques, RK Olsen, P Bross… - Current medicinal …, 2010 - ingentaconnect.com
Riboflavin, commonly known as vitamin B2, is the precursor of flavin cofactors. It is present in
our typical diet, and inside the cells it is metabolized to FMN and FAD. As a result of their …

[引用][C] Riboflavin

DB McCormick - Present knowledge in nutrition, 2012 - Wiley Online Library
This chapter contains sections titled: Summary Introduction Natural Flavins Flavocoenzyme
Types and Functions Absorption, Transport, and Uptake Coenzyme Formations and …