Reduced glomerular filtration rate defines chronic kidney disease and is associated with
cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide …

Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …

Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-
decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci …

Chronic kidney disease (CKD) affects~ 10% of the global population, with considerable
ethnic differences in prevalence and aetiology. We assemble genome-wide association …

Genes underneath signals from genome-wide association studies (GWAS) for kidney
function are promising targets for functional studies, but prioritizing variants and genes is …

Chronic kidney disease (CKD) is a growing health burden currently affecting 10–15% of
adults worldwide. Estimated glomerular filtration rate (eGFR) as a marker of kidney function …

A previous meta-analysis of genome-wide association data by the Cohorts for Heart and
Aging Research in Genomic Epidemiology and CKDGen consortia identified 16 loci …

Chronic kidney disease (CKD) is common, affecting about 10% of the general population,
and causing significant morbidity and mortality. Apart from the risk conferred by traditional …

Chronic kidney disease (CKD), defined by low estimated glomerular filtration rate (eGFR),
contributes to global morbidity and mortality. Here we conduct a transethnic Genome-Wide …

The past 3 years have witnessed a dramatic expansion in our knowledge of the genetic
determinants of estimated glomerular filtration rate (eGFR) and chronic kidney disease …