Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: a review of possible mechanisms

C Calpe-López, MP García-Pardo, MA Aguilar - Molecules, 2019 - mdpi.com
Currently, there are no approved pharmacotherapies for addiction to cocaine and other
psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a …

Cannabidiol and substance use disorder: Dream or reality

S Karimi-Haghighi, Y Razavi, D Iezzi, AF Scheyer… - …, 2022 - Elsevier
Background Cannabidiol (CBD) is one of the major constituents of Cannabis sativa L. that
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …

[HTML][HTML] Cannabidiol prevents several of the behavioral alterations related to cocaine addiction in mice

JC Ledesma, C Manzanedo, MA Aguilar - Progress in Neuro …, 2021 - Elsevier
Cocaine dependence is a highly prevalent disease in modern society and lacks an effective
treatment. Cannabidiol (CBD), a major non-psychoactive constituent of Cannabis sativa, has …

Role of cannabidiol in the therapeutic intervention for substance use disorders

F Navarrete, MS García-Gutiérrez… - Frontiers in …, 2021 - frontiersin.org
Drug treatments available for the management of substance use disorders (SUD) present
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …

[HTML][HTML] Evaluation of the potential use of cannabidiol in the treatment of cocaine use disorder: A systematic review

LA Rodrigues, MES Caroba, FK Taba, R Filev… - Pharmacology …, 2020 - Elsevier
Background Cannabinoids may have an important therapeutic potential for the treatment of
dependence on crack cocaine. Cannabidiol (CBD), in particular, has anxiolytic …

Cannabidiol as an intervention for addictive behaviors: a systematic review of the evidence

M Prud'homme, R Cata… - … abuse: research and …, 2015 - journals.sagepub.com
Drug addiction is a chronically relapsing disorder characterized by the compulsive desire to
use drugs and a loss of control over consumption. Cannabidiol (CBD), the second most …

Cannabidiol in the context of substance use disorder treatment: A systematic review

V Paulus, J Billieux, A Benyamina, L Karila - Addictive behaviors, 2022 - Elsevier
Introduction Cannabidiol (CBD) is a phytocannabinoid found in the Cannabis plant. CBD
has received significant medical attention in relation to its anticonvulsant, anxiolytic, and …

Repeated Cannabidiol treatment reduces cocaine intake and modulates neural proliferation and CB1R expression in the mouse hippocampus

MÁ Luján, A Castro-Zavala, L Alegre-Zurano… - …, 2018 - Elsevier
Cannabinoid derivatives have shown promising results for treating neuropsychiatric
disorders, including drug addiction. Recent studies on the therapeutic effects of Cannabidiol …

Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle

G Gonzalez-Cuevas, R Martin-Fardon… - …, 2018 - nature.com
Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa, has
received attention for therapeutic potential in treating neurologic and psychiatric disorders …

Cannabidiol prevents priming-and stress-induced reinstatement of the conditioned place preference induced by cocaine in mice

C Calpe-López, A Gasparyan… - Journal of …, 2021 - journals.sagepub.com
Background: Cocaine dependence is an important problem without any effective
pharmacological treatment. Some preclinical studies have suggested that cannabidiol …