Regulation of TSH Receptor Autoantibodies by a long Non-Coding RNA (Heg) and Cdk1-A Review

NJ Christensen, G Habekost… - British Journal of …, 2013 - research.sdpublishers.net
Aims: A substantial part of the genome is transcribed in non-coding RNAs. We review our
finding of a long non-coding RNA (designated Heg) in mononuclear cells (MNC) and …

Decrease in TSH receptor autoantibodies during antithyroid treatment: relationship with a long noncoding Heg RNA and Cdk1 mRNA in mononuclear cells

NJ Christensen, G Habekost… - International Scholarly …, 2011 - Wiley Online Library
We have previously shown that a long noncoding RNA transcript Heg is negatively
correlated with TSH receptor autoantibodies (TRAb) in patients with untreated Graves …

Detection and characterization of autoantibodies blocking the TSH-dependent cAMP production using FRTL-5 cells

L Chiovato, P Vitti, A Lombardi, G Lopez… - Journal of …, 1987 - Springer
Autoantibodies blocking the TSH-stimulated cAMP production (TBkAb) were measured in
immunoglobulin G (IgG) preparations from 38 patients with primary autoimmune …

Affinity purification and diagnostic use of TSH receptor autoantibodies from human serum

NG Morgenthaler, WB Minich, M Willnich… - Molecular and cellular …, 2003 - Elsevier
Purification of TSH receptor autoantibodies (TRAb) from the serum of patients with Graves'
disease (GD) might help to elucidate the nature of these disease causing autoantibodies …

Autoimmunity and thyroid growth. Where do we stand?

HA Drexhage - European journal of endocrinology, 1996 - academic.oup.com
Autoimmunity and thyroid growth. Where do we stand? Page 1 Autoimmunity and thyroid
growth. Where do we stand? HA Drexhage This issue of European Journal of …

Tumour necrosis factor synergises with gamma interferon on the induction of mRNA for DR alpha chain on thyrocytes from Graves' disease and non toxic goitre

AM Kissonerghis, B Grubeck-Loebenstein, K Pirich… - …, 1989 - Taylor & Francis
In both thyroid autoimmune diseases Graves' and Hashimoto's thyroiditis, the epithelial
thyroid follicular cells (TFC) have been shown to express HLA class II molecules, and can …

The significance of immune-related molecule expression profiles in an animal model of Graves' disease

F Ye, P Hou, X Wu, X Ma, L Gao, L Wu, L Xu, B Shi - Autoimmunity, 2012 - Taylor & Francis
Background: The thyrotropin receptor (TSHR) A-subunit has been reported to be a critical
autoantigen in the generation of thyroid-stimulating antibodies, thereby causing Graves' …

Human anti TSHR antibodies

B Rees-Smith, J Sanders, J Furmaniak - US Patent 9,073,992, 2015 - Google Patents
US9073992B2 - Human anti TSHR antibodies - Google Patents US9073992B2 - Human anti
TSHR antibodies - Google Patents Human anti TSHR antibodies Download PDF Info Publication …

TSH-receptor autoantibodies in patients with chronic thyroiditis and hypothyroidism

M Giannone, M Dalla Costa, C Sabbadin… - Clinical Chemistry and …, 2022 - degruyter.com
Objectives The reported prevalence of TSH-receptor (TSHR) autoantibodies (TRAb) in
patients with chronic thyroiditis (CT) range from 0 to 48%. The objective was to study the …

Anti-TSH receptor antibodies in Graves' disease modulate the kinetic behaviour of autologous thyroid TSH receptors. Evidence of the IgG-induced cross-linkage of …

TWA de Bruin, D van der Heide… - European Journal of …, 1984 - academic.oup.com
The effect of the anti-TSH receptor antibodies present in the sera of 8 patients with Graves'
disease on the affinity constant (Ka) and the number (R) of TSH receptors in autologous …