The synucleins are a family of natively unfolded (or intrinsically unstructured) proteins
consisting of α-, β-, and γ-synuclein involved in neurodegenerative diseases and cancer …

α-Synuclein is an abundant presynaptic brain protein, misfolding, aggregation and
fibrillation of which are implicated as critical factors in several neurodegenerative diseases …

The synuclein family consists of three distinct highly homologous genes, α‐synuclein, β‐
synuclein, and γ‐synuclein, which have so far been found only in vertebrates. Proteins …

Synucleins are small naturally unfolded proteins involved in neurodegenerative diseases
and cancer. The family contains three members: α-, β-, and γ-synuclein. α-Synuclein is the …

Synucleins are small, soluble proteins expressed primarily in neural tissues and certain
tumors. The family includes three known proteins: α‐synuclein, β‐synuclein, and γ …

The human synuclein (syn) family is comprised of α-, β-, and γ-syn proteins. α-syn has the
highest propensity for aggregation, and its aggregated forms accumulate in Lewy bodies …

Parkinson's disease belongs to a group of currently incurable neurodegenerative disorders
characterized by the misfolding and accumulation of alpha‐synuclein aggregates that are …

α-Synuclein belongs to a small group of natively unfolded proteins that can transiently bind
to lipid membranes and acquire a partial α-helical conformation. Under certain pathogenic …

Protein misfolding and aggregation is a ubiquitous phenomenon associated with a wide
range of diseases. The synuclein family comprises three small naturally unfolded proteins …

The synucleinopathies, which include Parkinson's disease, dementia with Lewy bodies, and
multiple system atrophy, are a class of human neurodegenerative disorders unified by the …