Recent advances in the mechanisms of lung alveolarization and the pathogenesis of bronchopulmonary dysplasia

DMG Silva, C Nardiello, A Pozarska… - American Journal of …, 2015 - journals.physiology.org
Alveolarization is the process by which the alveoli, the principal gas exchange units of the
lung, are formed. Along with the maturation of the pulmonary vasculature, alveolarization is …

Recent advances in our understanding of the mechanisms of lung alveolarization and bronchopulmonary dysplasia

E Lignelli, F Palumbo, D Myti… - American Journal of …, 2019 - journals.physiology.org
Bronchopulmonary dysplasia (BPD) is the most common cause of morbidity and mortality in
preterm infants. A key histopathological feature of BPD is stunted late lung development …

Recent advances in our understanding of the mechanisms of late lung development and bronchopulmonary dysplasia

DE Surate Solaligue… - … of Physiology-Lung …, 2017 - journals.physiology.org
The objective of lung development is to generate an organ of gas exchange that provides
both a thin gas diffusion barrier and a large gas diffusion surface area, which concomitantly …

Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasia

J Bourbon, O Boucherat, B Chailley-Heu… - Pediatric research, 2005 - nature.com
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in very premature
infants and is characterized by impaired alveologenesis. This ultimate phase of lung …

Bronchopulmonary dysplasia: new insights

N Ambalavanan, WA Carlo - Clinics in perinatology, 2004 - perinatology.theclinics.com
Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease that occurs in infants,
usually in preterm infants receiving respiratory support with mechanical ventilation or …

Recent advances in late lung development and the pathogenesis of bronchopulmonary dysplasia

A Madurga, I Mižíková… - American Journal of …, 2013 - journals.physiology.org
In contrast to early lung development, a process exemplified by the branching of the
developing airways, the later development of the immature lung remains very poorly …

Aberrant signaling pathways of the lung mesenchyme and their contributions to the pathogenesis of bronchopulmonary dysplasia

SK Ahlfeld, SJ Conway - Birth Defects Research Part A: Clinical …, 2012 - Wiley Online Library
Bronchopulmonary dysplasia (BPD) is a chronic lung disease in infants born extremely
preterm, typically before 28 weeks' gestation, characterized by a prolonged need for …

Altered lung development in bronchopulmonary dysplasia

A Hadchouel, ML Franco‐Montoya… - Birth Defects Research …, 2014 - Wiley Online Library
Bronchopulmonary dysplasia (BPD) is the main respiratory sequela of extreme prematurity.
Its pathophysiology is complex, involving interactions between host and environment, likely …

Regulation of alveologenesis: clinical implications of impaired growth

C Galambos, DE DeMello - Pathology, 2008 - Taylor & Francis
During its development that begins in intrauterine life, the lung is transformed from a simple
epithelial lined sac that emerges from the foregut into a complex arrangement of blood …

Recent advances in the pathogenesis of BPD

RE Morty - Seminars in perinatology, 2018 - Elsevier
Bronchopulmonary dysplasia (BPD) continues to be one of the most common complications
of preterm birth and is characterized histopathologically by impaired lung alveolarization …