Long QT syndrome: genetics and future perspective
Long QT syndrome (LQTS) is an inherited primary arrhythmia syndrome that may present
with malignant arrhythmia and, rarely, risk of sudden death. The clinical symptoms include …
with malignant arrhythmia and, rarely, risk of sudden death. The clinical symptoms include …
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
AL Lahti, VJ Kujala, H Chapman… - Disease models & …, 2012 - journals.biologists.com
Long QT syndrome (LQTS) is caused by functional alterations in cardiac ion channels and is
associated with prolonged cardiac repolarization time and increased risk of ventricular …
associated with prolonged cardiac repolarization time and increased risk of ventricular …
Inherited long QT syndromes: a paradigm for understanding arrhythmogenesis
DM Roden, PM Spooner - Journal of Cardiovascular …, 1999 - Wiley Online Library
LQTS as a Paradigm. The inherited long QT syndrome (LQTS) is a familial disease
characterized by QT interval changes that often are labile, syncope, and sudden death due …
characterized by QT interval changes that often are labile, syncope, and sudden death due …
Long QT syndrome: novel insights into the mechanisms of cardiac arrhythmias
RS Kass, AJ Moss - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
The congenital long QT syndrome is a rare disorder in which mutation carriers are at risk for
polymorphic ventricular tachycardia and/or sudden cardiac death. Discovery and analysis of …
polymorphic ventricular tachycardia and/or sudden cardiac death. Discovery and analysis of …
Long QT syndrome
I Goldenberg, W Zareba, AJ Moss - Current problems in cardiology, 2008 - Elsevier
The hereditary Long QT syndrome (LQTS) is a genetic channelopathy with variable
penetrance that is associated with increased propensity for polymorphic ventricular …
penetrance that is associated with increased propensity for polymorphic ventricular …
Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
E Matsa, D Rajamohan, E Dick, L Young… - European heart …, 2011 - academic.oup.com
Aims Congenital long QT syndromes (LQTSs) are associated with prolonged ventricular
repolarization and sudden cardiac death. Limitations to existing clinical therapeutic …
repolarization and sudden cardiac death. Limitations to existing clinical therapeutic …
[HTML][HTML] Long QT syndrome
M Alders, H Bikker, I Christiaans - 2018 - europepmc.org
Long QT syndrome (LQTS) is a cardiac electrophysiologic disorder, characterized by QT
prolongation and T-wave abnormalities on the EKG that are associated with …
prolongation and T-wave abnormalities on the EKG that are associated with …
Diagnosis, management and therapeutic strategies for congenital long QT syndrome
AAM Wilde, AS Amin, PG Postema - Heart, 2022 - heart.bmj.com
Congenital long QT syndrome (LQTS) is characterised by heart rate corrected QT interval
prolongation and life-threatening arrhythmias, leading to syncope and sudden death …
prolongation and life-threatening arrhythmias, leading to syncope and sudden death …
Long QT syndrome
GM Vincent - Cardiology clinics, 2000 - Elsevier
The long QT syndrome (LQTS) is a disorder of cardiac ion channels that affect
repolarization. The characteristic manifestations are prolongation of the QT interval and T …
repolarization. The characteristic manifestations are prolongation of the QT interval and T …
[HTML][HTML] Patient-specific induced pluripotent stem-cell models for long-QT syndrome
Background Long-QT syndromes are heritable diseases associated with prolongation of the
QT interval on an electrocardiogram and a high risk of sudden cardiac death due to …
QT interval on an electrocardiogram and a high risk of sudden cardiac death due to …