Engineered nucleic acids and methods of use thereof

JP Schrum, S Bancel, NB Afeyan - US Patent 8,822,663, 2014 - Google Patents
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …

Engineered nucleic acids and methods of use thereof

JP Schrum, GJ Sieczkiewicz, K Ejebe… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
45893552&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Engineered nucleic acids and methods of use thereof for non-human vertebrates

NB Afeyan, G Sieczkiewicz, S Bancel - US Patent App. 14/117,890, 2014 - Google Patents
Described herein are compositions, methods, pro cesses, kits and devices for the design,
preparation, manufac ture and/or formulation of modified nucleic acid or enhanced nucleic …

Engineered nucleic acids and methods of use thereof

JP Schrum, S Bancel, NB Afeyan - US Patent 9,181,319, 2015 - Google Patents
A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, eg
guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as …

Artificial nucleic acid molecules for improved protein or peptide expression

A Thess - US Patent 9,683,233, 2017 - Google Patents
DBFUQOZREOHGAV-UAKXSSHOSA-N [[(2r, 3s, 4r, 5r)-5-(4-amino-5-bromo-2-oxopyrimidin-
1-yl)-3, 4-dihydroxyoxolan-2-yl] methoxy-hydroxyphosphoryl] phosphono hydrogen …

Polynucleotide molecules and uses thereof

AW Fraley, A Roy, M Stanton - US Patent 10,385,088, 2019 - Google Patents
US10385088B2 - Polynucleotide molecules and uses thereof - Google Patents
US10385088B2 - Polynucleotide molecules and uses thereof - Google Patents …

Engineered nucleic acids and methods of use thereof

S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …

RNA-Guided Human Genome Engineering

GM Church, L Yang - US Patent App. 14/318,933, 2014 - Google Patents
Filed: Jun. 30, 2014 A method of altering a eukaryotic cell is provided including transfecting
the eukaryotic cell with a nucleic acid encoding Related US Application Data RNA …

Nucleic acid constructs and methods of use

MS Chee - US Patent 10,266,884, 2019 - Google Patents
5, 512, 439 A 6, 013, 440 A 6, 143, 496 A 6, 153, 389 A 6, 210, 894 B1 6, 258, 558 B1 6,
261, 804 B1 6, 281, 804 B1 6, 344, 316 B1 6, 404, 907 B1 6, 416, 950 B1 6, 485, 982 B1 6 …

Nucleic acid constructs and methods of use

MS Chee - US Patent 9,085,798, 2015 - Google Patents
US9085798B2 - Nucleic acid constructs and methods of use - Google Patents
US9085798B2 - Nucleic acid constructs and methods of use - Google Patents Nucleic acid …