Microbubbles for human diagnosis and therapy

L Fournier, T de La Taille, C Chauvierre - Biomaterials, 2023 - Elsevier
Microbubbles (MBs) were observed for the first time in vivo as a curious consequence of
quick saline injection during ultrasound (US) imaging of the aortic root, more than 50 years …

Microbubbles in imaging: applications beyond ultrasound

P Kogan, RC Gessner, PA Dayton - Bubble Science, Engineering & …, 2010 - Taylor & Francis
Since their introduction as ultrasound contrast agents, microbubbles have demonstrated the
potential to revolutionise the use of ultrasound at the bedside. Aside from clinical …

Microbubbles in medical imaging: current applications and future directions

JR Lindner - Nature reviews Drug discovery, 2004 - nature.com
Not all bubbles in the bloodstream are detrimental. During the past decade, contrast-
enhanced ultrasound has evolved from a purely investigational tool to a routine diagnostic …

Microbubbles as ultrasound contrast agents for molecular imaging: preparation and application

S Unnikrishnan, AL Klibanov - American journal of …, 2012 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this review is to describe trends in microbubble application in
molecular imaging. CONCLUSION. Microbubbles are used for contrast ultrasound imaging …

Recent advances in molecular, multimodal and theranostic ultrasound imaging

F Kiessling, S Fokong, J Bzyl, W Lederle… - Advanced drug delivery …, 2014 - Elsevier
Ultrasound (US) imaging is an exquisite tool for the non-invasive and real-time diagnosis of
many different diseases. In this context, US contrast agents can improve lesion delineation …

Targeted microbubbles in the experimental and clinical setting

A Alzaraa, G Gravante, WY Chung, D Al-Leswas… - The American journal of …, 2012 - Elsevier
BACKGROUND: Microbubbles have improved ultrasonography imaging techniques over the
past 2 decades. Their safety, versatility, and easiness of use have rendered them equal or …

[PDF][PDF] Ultrasound microbubble contrast agents for diagnostic and therapeutic applications: current status and future design

CK Yeh - Chang Gung Med J, 2012 - researchgate.net
Ultrasound contrast agents are highly echogenic microbubbles with many unique properties.
Microbubbles can basically improve the sensitivity of conventional ultrasound imaging to the …

Microbubble compositions, properties and biomedical applications

SR Sirsi, MA Borden - Bubble Science, Engineering & Technology, 2009 - Taylor & Francis
Over the last decade, there has been a significant progress towards the development of
microbubbles as theranostics for a wide variety of biomedical applications. The unique …

Ultrasound microbubble contrast agents: fundamentals and application to gene and drug delivery

K Ferrara, R Pollard, M Borden - Annu. Rev. Biomed. Eng., 2007 - annualreviews.org
This review offers a critical analysis of the state of the art of medical microbubbles and their
application in therapeutic delivery and monitoring. When driven by an ultrasonic pulse …

[HTML][HTML] In vivo biological fate of poly (vinylalcohol) microbubbles in mice

B Cerroni, R Cicconi, L Oddo, M Scimeca, R Bonfiglio… - Heliyon, 2018 - cell.com
Microbubbles (MBs) are used in clinical practice as vascular ultrasound contrast agents, and
are gaining popularity as a platform supporting multimodal imaging and targeted therapy …