[HTML][HTML] Application-specific approaches to MicroCT for evaluation of mouse models of pulmonary disease

EF Redente, KW Kopf, AN Bahadur, A Robichaud… - Plos one, 2023 - journals.plos.org
The advent of micro-computed tomography (microCT) has provided significant advancement
in our ability to generate clinically relevant assessments of lung health and disease in small …

Longitudinal micro-CT provides biomarkers of lung disease and therapy in preclinical models, thereby revealing compensatory changes in lung volume

GV Velde, J Poelmans, E De Langhe… - Dis. Model …, 2016 - journals.biologists.com
Obstructive, interstitial, infectious and malignant lung diseases remain among the most
important health challenges and novel or improved therapeutic strategies are essential for …

Longitudinal in vivo microcomputed tomography of mouse lungs: No evidence for radiotoxicity

G Vande Velde, E De Langhe… - … of Physiology-Lung …, 2015 - journals.physiology.org
Before microcomputed tomography (micro-CT) can be exploited to its full potential for
longitudinal monitoring of transgenic and experimental mouse models of lung diseases …

[PDF][PDF] Automated quantitative analysis of a mouse model of chronic pulmonary inflammation using micro X-ray computed tomography

X Artaechevarria, D Pérez-Martín… - Medical Image …, 2010 - researchgate.net
Micro-CT has emerged as an excellent tool for in-vivo imaging of the lungs of small
laboratory animals. Several studies have shown that it can be used to assess the evolution …

Imaging the mouse lung with micro-CT

W Recheis, G McLennan, AF Ross… - Lung biology in …, 2005 - api.taylorfrancis.com
Computed tomography (CT) of the lung has made major advances in hardware and software
over the last decade. The human lung can now be imaged rapidly and volumetrically, with …

Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory …

G Vande Velde, J Poelmans… - Disease models & …, 2016 - journals.biologists.com
In vivo lung micro-computed tomography (micro-CT) is being increasingly embraced in
pulmonary research because it provides longitudinal information on dynamic disease …

[HTML][HTML] Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography

E De Langhe, G Vande Velde, J Hostens… - 2012 - journals.plos.org
Background In vivo high-resolution micro-computed tomography allows for longitudinal
image-based measurements in animal models of lung disease. The combination of …

Imaging techniques for small animal imaging models of pulmonary disease: micro-CT

KA Johnson - Toxicologic pathology, 2007 - journals.sagepub.com
Microcomputed tomography (micro-CT) is ideal for quantifying pulmonary disease because
of the inherent contrast between tissue and air that exists in the lungs. Both in vivo and in …

Quantifying lung morphology with respiratory-gated micro-CT in a murine model of emphysema

NL Ford, EL Martin, JF Lewis… - Physics in Medicine …, 2009 - iopscience.iop.org
Non-invasive micro-CT imaging techniques have been developed to investigate lung
structure in free-breathing rodents. In this study, we investigate the utility of retrospectively …

Optimized murine lung preparation for detailed structural evaluation via micro-computed tomography

DM Vasilescu, L Knudsen, M Ochs… - Journal of Applied …, 2012 - journals.physiology.org
Utilizing micro-X-ray CT (μCT) imaging, we sought to generate an atlas of in vivo and
intact/ex vivo lungs from normal murine strains. In vivo imaging allows visualization of …