[HTML][HTML] Nanoparticles surface chemistry influence on protein corona composition and inflammatory responses

LE González-García, MN MacGregor, RM Visalakshan… - Nanomaterials, 2022 - mdpi.com
Nanoparticles are widely used for biomedical applications such as vaccine, drug delivery,
diagnostics, and therapeutics. This study aims to reveal the influence of nanoparticle surface …

Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity

YK Lee, EJ Choi, TJ Webster, SH Kim… - International journal of …, 2015 - Taylor & Francis
Although the cytotoxicity of nanoparticles (NPs) is greatly influenced by their interactions
with blood proteins, toxic effects resulting from blood interactions are often ignored in the …

Corona of thorns: the surface chemistry-mediated protein corona perturbs the recognition and immune response of macrophages

R Cai, J Ren, Y Ji, Y Wang, Y Liu, Z Chen… - … applied materials & …, 2019 - ACS Publications
The significance of protein coronas on the biological fates of nanoparticles has been widely
recognized. Therefore, the alterations on biological effects caused by protein coronas need …

Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles

C Gunawan, M Lim, CP Marquis, R Amal - Journal of Materials …, 2014 - pubs.rsc.org
Upon contact with plasma or other protein-containing biological fluids, the surface of
nanoparticles is immediately decorated with proteins forming a biologically active protein …

Impact of silica nanoparticle surface chemistry on protein corona formation and consequential interactions with biological cells

A Kurtz-Chalot, C Villiers, J Pourchez… - Materials Science and …, 2017 - Elsevier
Nanoparticles (NP) physico-chemical features greatly influence NP/cell interactions. NP
surface functionalization is often used to improve NP biocompatibility or to enhance cellular …

Protein precoating modulates biomolecular coronas and nanocapsule–immune cell interactions in human blood

S Li, Y Ju, J Zhou, M Faria, CS Ang… - Journal of Materials …, 2022 - pubs.rsc.org
The biomolecular corona that forms on particles upon contact with blood plays a key role in
the fate and utility of nanomedicines. Recent studies have shown that precoating …

[HTML][HTML] Tuning the immune system by nanoparticle–biomolecular corona

V Palmieri, G Caracciolo - Nanoscale Advances, 2022 - pubs.rsc.org
Nanotechnology has a great potential to revolutionize the landscape of medicine, but an
inadequate understanding of the nanomaterial-biological (nano–bio) interface hampers its …

The concept of bio-corona in modulating the toxicity of engineered nanomaterials (ENM)

D Westmeier, RH Stauber, D Docter - Toxicology and applied …, 2016 - Elsevier
Besides the wide use of engineered nanomaterials (ENM) in technical products, their
application spectrum in biotechnology and biomedicine is steadily increasing. In complex …

[HTML][HTML] Merging worlds of nanomaterials and biological environment: factors governing protein corona formation on nanoparticles and its biological consequences

P Foroozandeh, AA Aziz - Nanoscale Research Letters, 2015 - Springer
Protein corona has became a prevalent subject in the field of nanomedicine owing to its
diverse role in determining the efficiency, efficacy, and the ultimate biological fate of the …

Stealth effect of biomolecular corona on nanoparticle uptake by immune cells

G Caracciolo, S Palchetti, V Colapicchioni… - Langmuir, 2015 - ACS Publications
When injected in a biological milieu, a nanomaterial rapidly adsorbs biomolecules forming a
biomolecular corona. The biomolecular corona changes the interfacial composition of a …