Cell-replacement therapies have long been an attractive prospect for treating Parkinson
disease. However, the outcomes of fetal tissue-derived cell transplants in individuals with …

Treating neurodegenerative diseases with cell transplantation has been within reach since
the first pioneering clinical trials in which dopamine neuron progenitors from the fetal brain …

In Parkinson's disease (PD), there are currently no effective therapies to prevent or slow
down disease progression. Cell replacement therapy using human pluripotent stem cell …

Parkinson disease (PD) is characterized by loss of the A9 nigral neurons that provide
dopaminergic innervation to the striatum. This discovery led to the successful instigation of …

Background Stem cells hold tremendous promise for regenerative medicine because they
can be expanded infinitely, giving rise to large numbers of differentiated cells required for …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which
affects about 0.3% of the general population. As the population in the developed world ages …

Current therapeutic approaches for Parkinson's disease (PD) provide symptomatic relief but
none of them change the course of disease. There is therefore a clear need for regenerative …

Recent news of an impending clinical cell transplantation trial in Parkinson's disease using
parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient …

Stem cell-based therapies for Parkinson's disease are moving into a new and exciting era,
with several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived …

During the past 40 years brain tissue grafting techniques have been used both to study
fundamental neurobiological questions and to treat neurological diseases. Motor symptoms …