CD44 enhances the epithelial-mesenchymal transition in association with colon cancer invasion

SH Cho, YS Park, HJ Kim, CH Kim… - International …, 2012 - spandidos-publications.com
The metastatic process involves the migration and invasion of cancer cells throughout the
body to produce secondary tumors at distant sites. Through of epithelial-mesenchymal …

The role of CD44 in epithelial–mesenchymal transition and cancer development

H Xu, Y Tian, X Yuan, H Wu, Q Liu… - OncoTargets and …, 2015 - Taylor & Francis
CD44, a multi-structural and multifunctional transmembrane glycoprotein, was initially
identified as a receptor for hyaluronan that participates in both physiological and …

Role of CD44 isoforms in epithelial-mesenchymal plasticity and metastasis

M Primeaux, S Gowrikumar, P Dhawan - Clinical & experimental …, 2022 - Springer
Cellular plasticity lies at the core of cancer progression, metastasis, and resistance to
treatment. Stemness and epithelial-mesenchymal plasticity in cancer are concepts that …

[HTML][HTML] CD44: a multifunctional cell surface adhesion receptor is a regulator of progression and metastasis of cancer cells

LT Senbanjo, MA Chellaiah - Frontiers in cell and developmental …, 2017 - frontiersin.org
CD44 is a cell surface adhesion receptor that is highly expressed in many cancers and
regulates metastasis via recruitment of CD44 to the cell surface. Its interaction with …

CD44v6 expression is related to mesenchymal phenotype and poor prognosis in patients with colorectal cancer

S Saito, H Okabe, M Watanabe… - Oncology …, 2013 - spandidos-publications.com
CD44 standard isoform (CD44s) is a cancer stem cell marker in many tumors, and is one of
the CD44 isoforms. CD44v6 has been reported to correlate with tumor progression and poor …

Comparison of CD44 expression in primary tumours and metastases of colorectal cancer

R Bendardaf, A Algars, A Elzagheid… - Oncology …, 2006 - spandidos-publications.com
A better understanding on the development of a metastatic phenotype in colorectal cancer
(CRC) is essential to help identify patients at high risk for metastasis. Therefore, we have …

Heparan sulfate enhances invasion by human colon carcinoma cell lines through expression of CD44 variant exon 3

H Kuniyasu, N Oue, M Tsutsumi, E Tahara… - Clinical Cancer Research, 2001 - AACR
CD44 variant exon (CD44v) 3 is a heparan sulfate-binding isoform of CD44. The role of
CD44v3 in invasion and metastasis associated with heparan sulfate in colon cancer cell …

CD44s expression in human colon carcinomas influences growth of liver metastases

SH Choi, K Takahashi, H Eto, SS Yoon… - … journal of cancer, 2000 - Wiley Online Library
CD44 is a family of cell‐surface adhesion molecules which exist in several isoforms arising
from mRNA alternative. Malignant transformation of colonic mucosa is associated with …

CD44: More than a mere stem cell marker

I Morath, TN Hartmann, V Orian-Rousseau - The international journal of …, 2016 - Elsevier
CD44 is a cell adhesion molecule that plays an important role in tumor progression and
metastasis. The role of CD44 in tumorigenesis is due to its binding to extracellular matrix …

The CD44 adhesion molecule and metastasis

KK Tanabe, H Saya - Critical Reviews™ in Oncogenesis, 1994 - dl.begellhouse.com
The family of related cell surface adhesion molecules designated CD44 are multifunctional
proteins displayed by a wide variety of normal and malignant tissues. CD44 properties in …