Prognostic and predictive values of the immunoscore in patients with rectal cancer

MG Anitei, G Zeitoun, B Mlecnik, F Marliot… - Clinical Cancer …, 2014 - AACR
Purpose: To determine whether the tumor immune infiltrate, as recently evaluated with the
Immunoscore methodology, could be a useful prognostic marker in patients with rectal …

Rational bases for the use of the Immunoscore in routine clinical settings as a prognostic and predictive biomarker in cancer patients

A Kirilovsky, F Marliot, C El Sissy… - International …, 2016 - academic.oup.com
Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) tumor, nodes, metastasis (TNM) classification system based on tumor features …

Immune scores in colorectal cancer: Where are we?

D Malka, A Lièvre, T André, J Taïeb, M Ducreux… - European Journal of …, 2020 - Elsevier
There is growing evidence that the immune system may prevent the occurrence, growth and
metastatic diffusion of colorectal cancer (CRC). The role played by the adaptive immune …

[HTML][HTML] Analytical validation of the Immunoscore and its associated prognostic value in patients with colon cancer

F Marliot, X Chen, A Kirilovsky, T Sbarrato… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background New and fully validated tests need to be brought into clinical practice to improve
the estimation of recurrence risk in patients with colon cancer. The aim of this study was to …

Immunoscore and its introduction in clinical practice.

J Galon, A Lanzi - The Quarterly Journal of Nuclear Medicine and …, 2020 - europepmc.org
Current cancer classification is based on intrinsic tumor parameters such as characteristic of
tumor cells, tumor progression, tumor invasion and the presence of distant metastases, as …

Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction

B Mlecnik, M Tosolini, A Kirilovsky, A Berger… - Journal of clinical …, 2011 - ascopubs.org
Purpose The prognosis of patients with colorectal cancer has sometimes proved uncertain;
thus, the prognostic significance of immune criteria was compared with that of the tumor …

Multicenter international society for immunotherapy of cancer study of the consensus immunoscore for the prediction of survival and response to chemotherapy in …

B Mlecnik, C Bifulco, G Bindea, F Marliot… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE The purpose of this study was to evaluate the prognostic value of Immunoscore
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …

Immunoscore in mismatch repair‐proficient and‐deficient colon cancer

EV Wirta, T Seppälä, M Friman… - The Journal of …, 2017 - Wiley Online Library
The aim of this study was to investigate immune response and its prognostic significance in
colon carcinomas using the previously described Immunoscore (IS). A population‐based …

Validation of the Immunoscore (IM) as a prognostic marker in stage I/II/III colon cancer: Results of a worldwide consortium-based analysis of 1,336 patients.

J Galon, B Mlecnik, F Marliot, FS Ou, CB Bifulco… - 2016 - ascopubs.org
3500 Background: Mounting evidence indicates an enhanced lymphocytic reaction as an
informative prognostic indicator in colon cancer (CC). The IM methodology has been defined …

Prognostic and predictive value of the Immunoscore in stage III colon cancer patients treated with oxaliplatin in the prospective IDEA France PRODIGE-GERCOR …

F Pagès, T André, J Taieb, D Vernerey, J Henriques… - Annals of …, 2020 - Elsevier
Background The Immunoscore (IS), which prognostically classifies stage I–III colon cancer
(CC) patients, was evaluated in the International Duration Evaluation of Adjuvant Therapy …