Cardiovascular disease, a leading cause of mortality worldwide, is caused mainly by
atherosclerosis, a chronic inflammatory disease of blood vessels. Lesions of atherosclerosis …

Immune responses participate in every phase of atherosclerosis. There is increasing
evidence that both adaptive and innate immunity tightly regulate atherogenesis. Although …

Atherosclerosis is an inflammatory disease. This article reviews the emergence of this
concept from studies of patients and their lesions, experimental animal models, and …

According to the traditional view, atherosclerosis results from a passive buildup of
cholesterol in the artery wall. Yet, burgeoning evidence implicates inflammation and immune …

Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …

Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …

Traditional risk factors like hypercholesterolemia are important for atherogenesis, but it is
now apparent that the immune system also plays an important role. Uncovering the …

Atherosclerosis is an inflammatory disease with a significant autoimmune component.
Studies using transgenic murine models have clarified that recruitment of mononuclear …

This review considers critically the evidence for the involvement of mediators of innate and
acquired immunity in various stages of atherosclerosis. Rapidly mobilized arms of innate …

Cardiovascular disease is the leading cause of death in several countries. The underlying
process is atherosclerosis, a slowly progressing chronic disorder that can lead to …