Dual EGFR and COX-2 inhibition as a novel approach to targeting head and neck squamous cell carcinoma
J Kao, AT Sikora, S Fu - Current cancer drug targets, 2009 - ingentaconnect.com
Epidermal growth factor inhibition (EGFR) is emerging as an important treatment modality in
several epithelial malignancies, including head and neck squamous cell carcinoma …
several epithelial malignancies, including head and neck squamous cell carcinoma …
New strategies in head and neck cancer: understanding resistance to epidermal growth factor receptor inhibitors
LF Chen, EEW Cohen, JR Grandis - Clinical Cancer Research, 2010 - AACR
The epidermal growth factor receptor (EGFR) is a validated target in squamous cell
carcinoma of the head and neck (HNSCC). However, despite high expression of EGFR in …
carcinoma of the head and neck (HNSCC). However, despite high expression of EGFR in …
Anti‐epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistance
C Boeckx, M Baay, A Wouters, P Specenier… - The …, 2013 - academic.oup.com
Targeted therapy against the epidermal growth factor receptor (EGFR) is one of the most
promising molecular therapeutics for head and neck squamous cell carcinoma (HNSCC) …
promising molecular therapeutics for head and neck squamous cell carcinoma (HNSCC) …
[HTML][HTML] The challenge of blocking a wider family members of EGFR against head and neck squamous cell carcinomas
J Martinez-Useros, J Garcia-Foncillas - Oral oncology, 2015 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) represent 95% of head and neck cancer
with an incidence of over half a million people globally. The prognosis for patients with …
with an incidence of over half a million people globally. The prognosis for patients with …
Targeting epidermal growth factor receptor signaling in the treatment of head and neck cancer
I Astsaturov, RB Cohen, P Harari - Expert review of anticancer …, 2006 - Taylor & Francis
In this review, key aspects of epidermal growth factor receptor (EGFR) biology and the fruitful
translation of these fundamental findings into recent treatment advances in head and neck …
translation of these fundamental findings into recent treatment advances in head and neck …
Mechanisms of and therapeutic approaches for overcoming resistance to epidermal growth factor receptor (EGFR)-targeted therapy in squamous cell carcinoma of the …
KAR Price, EEW Cohen - Oral oncology, 2015 - Elsevier
The majority of squamous cell carcinoma of the head and neck (SCCHN) overexpress
epidermal growth factor receptor (EGFR), which has been associated with poor treatment …
epidermal growth factor receptor (EGFR), which has been associated with poor treatment …
Mechanisms of resistance to EGFR inhibitors in head and neck cancer
JB Cooper, EEW Cohen - Head & Neck: Journal for the …, 2009 - Wiley Online Library
Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that activates multiple
signaling pathways, including phosphatidylinositol‐3‐kinase/v‐AKT murine thymoma viral …
signaling pathways, including phosphatidylinositol‐3‐kinase/v‐AKT murine thymoma viral …
Targeting pathways mediating resistance to anti-EGFR therapy in squamous cell carcinoma of the head and neck
NP Campbell, TA Hensing, MK Bhayani… - Expert Review of …, 2016 - Taylor & Francis
Introduction: As epidermal growth factor receptor (EGFR) is overexpressed in approximately
90% of squamous cell carcinomas of the head and neck (SCCHN), several therapeutic …
90% of squamous cell carcinomas of the head and neck (SCCHN), several therapeutic …
Overcoming resistance to EGFR inhibitor in head and neck cancer: a review of the literature
G Rabinowits, RI Haddad - Oral oncology, 2012 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) affects over half a million people
worldwide. Despite advances in therapy, only half of the patients are alive in 5years …
worldwide. Despite advances in therapy, only half of the patients are alive in 5years …
Targeted therapies in head and neck cancer
PM Specenier, JB Vermorken - Targeted Oncology, 2007 - Springer
Over the past decade, the important role of different growth factors and their receptors and
signal transduction pathways in the genesis and progression of tumors has been well …
signal transduction pathways in the genesis and progression of tumors has been well …
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