Tumor microenvironment

TC Walser, J Yanagawa, E Garon, JM Lee… - … and Emerging Therapies, 2010 - Springer
While genetic changes are critical for the malignant transformation of epithelial cells, the
microenvironment in which the cells reside also governs carcinogenesis. Most tumors arise …

The microenvironment of lung cancer and therapeutic implications

V Mittal, T El Rayes, N Narula, TE McGraw… - Lung Cancer and …, 2016 - Springer
The tumor microenvironment (TME) represents a milieu that enables tumor cells to acquire
the hallmarks of cancer. The TME is heterogeneous in composition and consists of cellular …

The lung microenvironment: an important regulator of tumour growth and metastasis

NK Altorki, GJ Markowitz, D Gao, JL Port… - Nature Reviews …, 2019 - nature.com
Lung cancer is a major global health problem, as it is the leading cause of cancer-related
deaths worldwide. Major advances in the identification of key mutational alterations have led …

14 Microenvironment and Lung Cancer

TC Walser, EL Liclican, KJ O'Byrne… - … Thoracic Oncology E …, 2017 - books.google.com
• The pulmonary microenvironment represents a unique milieu in which lung carcinogenesis
proceeds in complicity with the four main components of the tumor microenvironment (TME) …

[图书][B] Inflammation and lung cancer

SM Dubinett - 2015 - Springer
The inflammatory tumor microenvironment (TME) has a multifaceted role in tumor initiation,
progression, and metastasis. Whereas genetic changes are critical for the malignant …

Inflammation and lung carcinogenesis: applying findings in prevention and treatment

KA Peebles, JM Lee, JT Mao, S Hazra… - Expert review of …, 2007 - Taylor & Francis
Lung carcinogenesis is a complex process requiring the acquisition of genetic mutations that
confer the malignant phenotype as well as epigenetic alterations that may be manipulated in …

Targeting the lung cancer microenvironment: harnessing host responses

MM Fuster - Molecular targeted therapy of lung cancer, 2017 - Springer
Understanding the host response to lung cancer is critical in the development of long-term
therapeutic responses and cures for advanced-stage disease. While state-of-the-art …

[HTML][HTML] Impact of tumor microenvironment on lung cancer

E Levantini - Frontiers in Oncology, 2023 - frontiersin.org
Lung cancer is the leading cause of cancer-related mortality worldwide. In 2022 the Cancer
Statistics Center calculated an estimated four new cases and one death per minute from …

Biological considerations in lung cancer

B Almand, DP Carbone - Thoracic Oncology, 2001 - Springer
Our understanding of lung cancer biology has rapidly expanded in recent years. Lung
cancer, unlike most human cancers, can be traced to an environmental risk factor in the …

[图书][B] Lung cancer and personalized medicine: Novel therapies and clinical management

A Ahmad, SM Gadgeel - 2016 - Springer
This is the second part of volume Lung Cancer and Personalized Medicine. Part I of this
volume, available as a separate book, discussed lung cancer as a disease, the available …