[HTML][HTML] Epigenetic control of mesenchymal stem cells orchestrates bone regeneration

X Wang, F Yu, L Ye - Frontiers in Endocrinology, 2023 - frontiersin.org
Recent studies have revealed the vital role of MSCs in bone regeneration. In both self-
healing bone regeneration processes and biomaterial-induced healing of bone defects …

Epigenetic regulation in mesenchymal stem cell aging and differentiation and osteoporosis

R Wang, Y Wang, L Zhu, Y Liu, W Li - Stem Cells International, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) are a reliable source for cell‐based regenerative medicine
owing to their multipotency and biological functions. However, aging‐induced systemic …

Epigenetic regulation of osteogenic differentiation of mesenchymal stem cells

G Fu, A Ren, Y Qiu, Y Zhang - Current stem cell research & …, 2016 - ingentaconnect.com
Mesenchymal stem cells (MSCs) are multipotent progenitors that have the abilities of
selfrenewal and multiple direction differentiation. The osteogenic potential of MSCs holds …

[HTML][HTML] Epigenetic therapy targeting bone marrow mesenchymal stem cells for age-related bone diseases

Y Zhao, J He, T Qiu, H Zhang, L Liao, X Su - Stem cell research & therapy, 2022 - Springer
As global aging accelerates, the prevention and treatment of age-related bone diseases are
becoming a critical issue. In the process of senescence, bone marrow mesenchymal stem …

Epigenetic regulation of mesenchymal stem cell homeostasis

BD Sui, CX Zheng, M Li, Y Jin, CH Hu - Trends in Cell Biology, 2020 - cell.com
Mesenchymal stem cells (MSCs) have putative roles in maintaining adult tissue health, and
the functional decline of MSCs has emerged as a crucial pathophysiological driver of …

Epigenetic regulation of mesenchymal stem cells: a focus on osteogenic and adipogenic differentiation

CM Teven, X Liu, N Hu, N Tang, SH Kim… - Stem cells …, 2011 - Wiley Online Library
Stem cells are characterized by their capability to self‐renew and terminally differentiate into
multiple cell types. Somatic or adult stem cells have a finite self‐renewal capacity and are …

Functional and molecular changes of MSCs in aging

W Kuang, X Xu, Y Cao, Y Xu, L Chen… - Current Stem Cell …, 2015 - ingentaconnect.com
Mesenchymal stem cells (MSCs) are ideal candidates for different cellular therapies due to
their simple isolation, extensive expansion potential, and low immunogenicity. For various …

Osteogenic differentiation of human marrow-derived mesenchymal stem cells

PJ Marie, O Fromigué - Regenerative medicine, 2006 - Taylor & Francis
Bone marrow-derived mesenchymal stem cells (MSCs) are adherent cells that differentiate
into chondroblasts, osteoblasts and adipocytes. In this short review, we summarize the …

The response of human mesenchymal stem cells to osteogenic signals and its impact on bone tissue engineering

R Siddappa, H Fernandes, J Liu… - Current stem cell …, 2007 - ingentaconnect.com
Bone tissue engineering using human mesenchymal stem cells (hMSCs) is a
multidisciplinary field that aims to treat patients with trauma, spinal fusion and large bone …

[HTML][HTML] Mesenchymal stem cells under epigenetic control–the role of epigenetic machinery in fate decision and functional properties

A Walewska, A Janucik, M Tynecka, M Moniuszko… - Cell Death & …, 2023 - nature.com
Mesenchymal stem cells (mesenchymal stromal cells, MSC) are multipotent stem cells that
can differentiate into cells of at least three mesodermal lineages, namely adipocytes …