Dual stimuli-responsive release of aptamer AS1411 decorated erlotinib loaded chitosan nanoparticles for non-small-cell lung carcinoma therapy
K Saravanakumar, A Sathiyaseelan… - Carbohydrate …, 2020 - Elsevier
The present work was developed the pH dependent-aptamer AS1411 (APT) decorated and
erlotinib (En) loaded chitosan nanoparticles (CSNPs) for promising non-small-cell lung …
erlotinib (En) loaded chitosan nanoparticles (CSNPs) for promising non-small-cell lung …
AS1411 aptamer-decorated biodegradable polyethylene glycol–poly (lactic-co-glycolic acid) nanopolymersomes for the targeted delivery of gemcitabine to non–small …
Molecularly targeted drug delivery systems represent a novel therapeutic strategy in the
treatment of different cancers. In the present study, we have developed gemcitabine (GEM) …
treatment of different cancers. In the present study, we have developed gemcitabine (GEM) …
Multi-functionalized chitosan nanoparticles for enhanced chemotherapy in lung cancer
Chemotherapy-based treatment for cancer has made great progress in the past decades.
However, there is still a big challenge for the treatment of lung cancer. Herein, a …
However, there is still a big challenge for the treatment of lung cancer. Herein, a …
Biodegradable nanoparticles mediated co-delivery of erlotinib (ELTN) and fedratinib (FDTN) toward the treatment of ELTN-resistant non-small cell lung cancer …
D Chen, F Zhang, J Wang, H He, S Duan… - Frontiers in …, 2018 - frontiersin.org
Background: Erlotinib (ELTN)-based targeted therapy as first-line treatment for epidermal
growth factor receptor (EGFR)-mutant lung cancers suffers from insufficient selectivity, side …
growth factor receptor (EGFR)-mutant lung cancers suffers from insufficient selectivity, side …
Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer
This study was aimed at developing a nanoparticle strategy to overcome acquired
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …
Chitosan cross-linked docetaxel loaded EGF receptor targeted nanoparticles for lung cancer cells
Lung cancer, associated with the up-regulated epidermal growth factor receptor (EGFR) led
to the development of EGFR targeted anticancer therapeutics. The biopolymeric …
to the development of EGFR targeted anticancer therapeutics. The biopolymeric …
Aptamer-conjugated chitosan-anchored liposomal complexes for targeted delivery of erlotinib to EGFR-mutated lung cancer cells
F Li, H Mei, X Xie, H Zhang, J Liu, T Lv, H Nie, Y Gao… - The AAPS journal, 2017 - Springer
Lung cancer is the leading cancer and has the highest death rate. The epidermal growth
factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib has had a promising response …
factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib has had a promising response …
Smart drug delivery of p-Coumaric acid loaded aptamer conjugated starch nanoparticles for effective triple-negative breast cancer therapy
AVA Mariadoss, K Saravanakumar… - International Journal of …, 2022 - Elsevier
The nano-drug delivery system utilizing the ligand functionalized nanoparticles have a
tremendous application in cancer therapeutics. The present study was aimed to fabricate the …
tremendous application in cancer therapeutics. The present study was aimed to fabricate the …
Targeted hyaluronic acid-based lipid nanoparticle for apigenin delivery to induce Nrf2-dependent apoptosis in lung cancer cells
S Mahmoudi, M Ghorbani, M Sabzichi… - Journal of Drug Delivery …, 2019 - Elsevier
Overexpression of nuclear factor E2–related factor 2 (Nrf2) contributes to the
chemotherapeutic resistance of non–small-cell lung cancer (NSCLC). Docetaxel (DTX) is …
chemotherapeutic resistance of non–small-cell lung cancer (NSCLC). Docetaxel (DTX) is …
Dual targeting pH responsive chitosan nanoparticles for enhanced active cellular internalization of gemcitabine in non-small cell lung cancer
Lung cancer (LC), related with the enhanced expression of epidermal growth factor receptor
(EGFR) and sialic acid binding receptors (glycan) brought about the development of EGFR …
(EGFR) and sialic acid binding receptors (glycan) brought about the development of EGFR …