Mechanosensitive channels (MS channels) are membrane proteins capable of responding
to mechanical stress over a wide dynamic range of external mechanical stimuli. In recent …

Piezo channels are deemed to constitute one of the most important family of
mechanosensing ion channels since their discovery in 2010. With recent advances in …

Mechanosensitive cation channels and Ca2+ influx through these channels play an
important role in the regulation of endothelial cell functions. Transient receptor potential …

Mechanosensitive Piezo ion channels were first reported in 2010 in a mouse neuroblastoma
cell line, opening up a new field for studying the composition and function of eukaryotic …

Transient receptor potential (TRP) ion channel superfamily is involved in sensing and
transmission of a broad variety of external or internal stimuli, including but not limited to …

A variety of cell types in pulmonary arteries (endothelial cells, fibroblasts, and smooth
muscle cells) are continuously exposed to mechanical stimulations such as shear stress and …

Introduction Asthma is a chronic lung disease influenced by environmental and inflammatory
triggers and involving complex signaling pathways across resident airway cells such as …

Introduction Clinical observations and animal models suggest a critical role for the dynamic
regulation of transmural pressure and peristaltic airway smooth muscle contractions for …

The ability of cells to sense and respond to their physical environment is fundamental to a
broad spectrum of biological processes. Cells express an array of force sensors that can …

The use of respiratory support strategies such as continuous positive airway pressure in
premature infants can substantially stretch highly compliant perinatal airways, leading to …