Summary Background The HYPO-RT-PC trial compared conventionally fractionated
radiotherapy with ultra-hypofractionated radiotherapy in patients with localised prostate …

Background Hypofractionated radiotherapy for prostate cancer has gained increased
attention due to its proposed high radiation-fraction sensitivity. Recent reports from studies …

Summary Background Patient-reported outcomes (PROs) might detect more toxic effects of
radiotherapy than do clinician-reported outcomes. We did a quality of life (QoL) substudy to …

Background Several studies have reported a low α to β ratio for prostate cancer, suggesting
that hypofractionation could enhance the biological tumour dose without increasing …

Background Studies have reported a low α/β ratio for prostate cancer, suggesting that
hypofractionation could enhance the biological tumour dose without increasing …

Background In 2007, we began the randomised phase 3 multicentre HYPRO trial to
investigate the effect of hypofractionated radiotherapy compared with conventionally …

Background Prostate cancer might have high radiation-fraction sensitivity that would give a
therapeutic advantage to hypofractionated treatment. We present a pre-planned analysis of …

Introduction To characterize the efficacy (5-year disease-free survival [DFS]) and safety
(incidence of grade 2+ late gastrointestinal or genitourinary toxicity) of ultrahypofractionated …

Context Technological advances in radiation therapy delivery have permitted the use of high-
dose-per-fraction radiation therapy (RT) for early-stage prostate cancer (PCa). Level 1 …

Purpose In the multicenter, phase 3, HYpofractionated irradiation for PROstate cancer trial,
hypofractionated (HF) radiation therapy was compared with conventionally fractionated (CF) …