Antibiotic heteroresistance is a phenotype in which a bacterial isolate contains
subpopulations of cells that show a substantial reduction in antibiotic susceptibility …

Many bacterial species and antibiotic classes exhibit heteroresistance, a phenomenon in
which a susceptible bacterial isolate harbors a resistant subpopulation that can grow in the …

When choosing antibiotics to treat bacterial infections, it is assumed that the susceptibility of
the target bacteria to an antibiotic is reflected by laboratory estimates of the minimum …

SUMMARY “Heteroresistance” describes a phenomenon where subpopulations of
seemingly isogenic bacteria exhibit a range of susceptibilities to a particular antibiotic …

For decades, mankind has dominated the battle against bacteria, yet the tide is slowly
turning. Our antibacterial strategies are becoming less effective, allowing bacteria to get the …

Background Heteroresistance refers to subpopulation-mediated differential antimicrobial
susceptibility within a clonal bacterial population. Usually, it designates a resistant …

In addition to their impressive, well-publicized and well-researched propensity to evolve and
acquire genetically determined mechanisms for resistance to antibiotics, bacteria that are …

Evolution of bacteria towards resistance to antimicrobial agents, including multidrug
resistance, is unavoidable because it represents a particular aspect of the general evolution …

Recent laboratory evolution studies have shown that upon repetitive antibiotic treatments,
bacterial populations will adapt and eventually became tolerant and resistant to the drug …

Antibiotic-resistant bacteria are a significant threat to human health, with one estimate
suggesting they will cause 10 million worldwide deaths per year by 2050, surpassing deaths …