Towards the immune proteome of Staphylococcus aureus–The anti-S. aureus antibody response

S Holtfreter, J Kolata, BM Bröker - International Journal of Medical …, 2010 - Elsevier
This review provides an overview of the antibody response against Staphylococcus aureus,
which challenges the adaptive immune system with a broad and highly variable antigen …

Immune proteomics of Staphylococcus aureus

BM Bröker, A van Belkum - Proteomics, 2011 - Wiley Online Library
Immune proteomics is an increasingly powerful tool for the investigation of the adaptive
immune response to natural encounters between micro‐organisms and their hosts. The …

Covering all the Bases: Preclinical Development of an Effective Staphylococcus aureus Vaccine

IL Scully, PA Liberator, KU Jansen… - Frontiers in …, 2014 - frontiersin.org
A key aspect of the pathogenesis of the Gram positive bacterium Staphylococcus aureus is
its ability to rapidly adapt to the host environment during the course of an infection. To …

Staphylococcus aureus: setting its sights on the human innate immune system

KD Buchan, SJ Foster, SA Renshaw - Microbiology, 2019 - microbiologyresearch.org
Staphylococcus aureus has colonized humans for at least 10 000 years, and today inhabits
roughly a third of the population. In addition, S. aureus is a major pathogen that is …

Staphylococcus aureus strategies to evade the host acquired immune response

O Goldmann, E Medina - International Journal of Medical Microbiology, 2018 - Elsevier
Staphylococcus aureus poses a significant public-health problem. Infection caused by S.
aureus can manifest as acute or long-lasting persistent diseases that are often refractory to …

The immune evasion roles of Staphylococcus aureus protein A and impact on vaccine development

A Bear, T Locke, S Rowland-Jones… - Frontiers in Cellular …, 2023 - frontiersin.org
While Staphylococcus aureus (S. aureus) bacteria are part of the human commensal flora,
opportunistic invasion following breach of the epithelial layers can lead to a wide array of …

Exploring Staphylococcus aureus pathways to disease for vaccine development

A DeDent, HK Kim, D Missiakas… - Seminars in …, 2012 - Springer
Staphylococcus aureus is a commensal of the human skin or nares and a pathogen that
frequently causes skin and soft tissue infections as well as bacteremia and sepsis. Recent …

Adaptive Immunity Against Staphylococcus aureus

H Karauzum, SK Datta - Staphylococcus aureus: Microbiology, Pathology …, 2017 - Springer
A complex interplay between host and bacterial factors allows Staphylococcus aureus to
occupy its niche as a human commensal and a major human pathogen. The role of …

A Comprehensive View on the Human Antibody Repertoire Against Staphylococcus aureus Antigens in the General Population

TC Meyer, S Michalik, S Holtfreter, S Weiss… - Frontiers in …, 2021 - frontiersin.org
Our goal was to provide a comprehensive overview of the antibody response to
Staphylococcus aureus antigens in the general population as a basis for defining disease …

Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non‐carriers

J Kolata, LGM Bode, S Holtfreter, L Steil, H Kusch… - …, 2011 - Wiley Online Library
Staphylococcus aureus is both a prominent cause of nosocomial infections with significant
morbidity and mortality and a commensal with nasal carriage in around 30% of the …