Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae

SA Henry, SD Kohlwein, GM Carman - Genetics, 2012 - academic.oup.com
Due to its genetic tractability and increasing wealth of accessible data, the yeast
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …

Regulation of Phospholipid Synthesis in the Yeast Saccharomyces cerevisiae

GM Carman, GS Han - Annual review of biochemistry, 2011 - annualreviews.org
The yeast Saccharomyces cerevisiae, with its full complement of organelles, synthesizes
membrane phospholipids by pathways that are generally common to those found in higher …

[HTML][HTML] Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p

TC Santiago, CB Mamoun - Journal of Biological Chemistry, 2003 - ASBMB
In Saccharomyces cerevisiae, genes encoding phospholipid-synthesizing enzymes are
regulated by inositol and choline (IC). The current model suggests that when these …

Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes

GM Carman, SA Henry - Progress in lipid research, 1999 - Elsevier
In this article, we will review recent progress in elucidating the mechanisms that regulate
phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and discuss advances in …

[HTML][HTML] The response to inositol: regulation of glycerolipid metabolism and stress response signaling in yeast

SA Henry, ML Gaspar, SA Jesch - Chemistry and physics of lipids, 2014 - Elsevier
This article focuses on discoveries of the mechanisms governing the regulation of
glycerolipid metabolism and stress response signaling in response to the phospholipid …

Transcriptional regulation of yeast phospholipid biosynthetic genes

M Chen, LC Hancock, JM Lopes - … et Biophysica Acta (BBA)-Molecular and …, 2007 - Elsevier
The last several years have been witness to significant developments in understanding
transcriptional regulation of the yeast phospholipid structural genes. The response of most …

[HTML][HTML] PAH1-encoded phosphatidate phosphatase plays a role in the growth phase-and inositol-mediated regulation of lipid synthesis in Saccharomyces cerevisiae

F Pascual, A Soto-Cardalda, GM Carman - Journal of Biological Chemistry, 2013 - ASBMB
In the yeast Saccharomyces cerevisiae, the synthesis of phospholipids in the exponential
phase of growth occurs at the expense of the storage lipid triacylglycerol. As exponential …

Genetic regulation of phospholipid metabolism: yeast as a model eukaryote

SA Henry, JL Patton-Vogt - Progress in nucleic acid research and …, 1998 - Elsevier
Baker's yeast, Saccharomyces cerevisiae, is an excellent and an increasingly important
model for the study of fundamental questions in eukaryotic cell biology and genetic …

[HTML][HTML] Coordination of storage lipid synthesis and membrane biogenesis: evidence for cross-talk between triacylglycerol metabolism and phosphatidylinositol …

ML Gaspar, HF Hofbauer, SD Kohlwein… - Journal of Biological …, 2011 - ASBMB
Despite the importance of triacylglycerols (TAG) and steryl esters (SE) in phospholipid
synthesis in cells transitioning from stationary-phase into active growth, there is no direct …

[HTML][HTML] Regulation of phospholipid synthesis in Saccharomyces cerevisiae by zinc

WM Iwanyshyn, GS Han, GM Carman - Journal of Biological Chemistry, 2004 - ASBMB
Zinc is an essential nutrient required for the growth and metabolism of eukaryotic cells. In
this work, we examined the effects of zinc depletion on the regulation of phospholipid …