Background Biotin interference in streptavidin-based immunoassays causes widespread
analytical distortions that may lead to clinical confusion, inappropriate patient management …

At present time, immunoassay systems, using fully automated platform, are the methods of
choice in the clinical laboratory, especially for the measurement of particularly complex …

Background Biotinylated antibodies and analogues are currently used in many
immunoassays while biotin is widely used as a dietary supplement. Thus, biotin interference …

Recently, biotin use as an oral supplement has increased significantly among the general
population. Biotin is a water soluble B-vitamin and is marketed to improve the cosmetic …

Objective: The objectives of this report are to review the mechanisms of biotin interference
with streptavidin/biotin-based immunoassays, identify automated immunoassay systems …

Despite sobering evidence of no benefit or even possible harm, the use of vitamin and
mineral supplements by adults continues to grow. It is estimated that the US supplement …

We read with interest the letter to the editor by Batista et al.[1] on the interference of biotin in
immunoassays. Biotin is available over the counter usually at strengths of 5 mg or less per …

Biotinylated antibodies/antigens are currently used in many immunoassay formats in clinical
settings for diversified analytes and biomarkers to offer high detection selectivity and …

We report on a 47 year old male patient with multiple sclerosis (MS) presenting in our
outpatient neurology clinic in Frankfurt/Main for therapy evaluation. Before change of …

Background Shifts in consumer behavior and clinical practice have increased reports of
biotin interference in immunoassays that incorporate biotin–streptavidin linkages in their …