Transcription is the process whereby RNA molecules are synthetized using DNA as the
template. In eukaryotic cells, this process is carried out by three different kinds of RNA …

Pervasive transcription is widespread and needs to be controlled in order to avoid
interference with gene expression. In Saccharomyces cerevisiae, the highly conserved …

Abstract RNA polymerase II (RNAPII) is responsible for the synthesis of a diverse set of RNA
molecules, including protein-coding messenger RNAs (mRNAs) and many short non-coding …

Transcription termination is essential to generate functional RNAs and to prevent disruptive
polymerase collisions resulting from concurrent transcription. The yeast Sen1p helicase is …

Summary RNA polymerase II (RNAPII) transcription involves initiation from a promoter,
transcriptional elongation through the gene, and termination in the terminator region. In …

Abstract RNA polymerase II (RNAPII)‐mediated gene transcription initiates at promoters and
ends at terminators. Transcription termination is intimately connected to 3′‐end processing …

RNA polymerase III (RNAPIII) synthesizes essential and abundant noncoding RNAs such as
transfer RNAs. Controlling RNAPIII span of activity by accurate and efficient termination is a …

Understanding the mechanism of transcription termination by a eukaryotic RNA polymerase
(RNAP) has been limited by lack of a characterizable intermediate that reflects transition …

Eukaryotic RNA polymerase III (pol III) transcribes short noncoding RNA genes such as
those encoding tRNAs, 5S rRNA, U6 snRNA, and a few others. As compared to its pol II …

Within a complex with Rai1, the 5′-3′ exoribonuclease Rat1 promotes termination of RNA
polymerase II (RNAPII) on protein-coding genes, but its underlying molecular mechanism is …