Background Tetramethylpyrazine, an alkaloid extracted from Ligusticum chuanxiong Hort
(Umbelliferae), has been used in China for cardiovascular and cerebrovascular diseases …

Puerarin (Pue), an isoflavone compound extracted from Pueraria, has been shown to inhibit
inflammation and reduce cerebral edema. The neuroprotective effect of puerarin has …

Background Previous studies have reported that puerarin possesses cardioprotective,
vasodilatory, anti-inflammatory, anti-apoptotic, and hypoglycemic properties. However, the …

The present study was designed to investigate the protective effect of eriodictyol on MCAO-
induced brain injury and its regulation of neural function and to explore the mechanism of its …

The aim of this study was to assess the underlying impact of Tetramethylpyrazine (TMP),
which is the main activity compound of Ligusticum chuanxiong Hort, on the blood–brain …

Background Sepsis associated encephalopathy (SAE) is a common but poorly understood
complication during sepsis. Currently, there are no preventive or therapeutic agents …

Ethnopharmacological relevanc Pyrolae herba (PH), a kind of Chinese herb, has been
identified to have an anti-inflammatory effect, while the potential for treating cognitive …

Sepsis is life-threatening organ dysfunction due to dysregulated systemic inflammatory and
immune response to infection, often leading to cognitive impairments. Growing evidence …

Results Our results depicted that resveratrol could reduce the cerebral edema caused by TBI
and improve the recovery of functional deficits in rats. Resveratrol was also able to …

Objective To explore whether the cholinergic anti-inflammatory pathway is involved in the
neuroprotective effect of acetylcholinesterase inhibitor huperzine A (HupA) on sepsis …