In SARS-CoV-2-infected humans, disease progression is often associated with acute
respiratory distress syndrome involving severe lung injury, coagulopathy, and thrombosis of …

COVID-19 progression often involves severe lung injury, inflammation, coagulopathy, and
leukocyte infiltration into pulmonary tissues. The pathogenesis of these complications is …

Microvascular thrombosis is associated with multiorgan failure and mortality in coronavirus
disease 2019 (COVID-19). Although thrombotic complications may be ascribed to the ability …

Among the pathways and mediators that may be dysregulated in COVID-19 infection, there
are proinflammatory cytokines, lymphocyte apoptosis, and the coagulation cascade. Venous …

Platelets are hyperactivated in coronavirus disease 2019 (COVID-19). However, the
mechanisms promoting platelet activation by severe acute respiratory syndrome coronavirus …

The universal phenomenon of blood clotting is well known to be protective in external
cellular/tissue injury. However, the emergence of unusual thrombotic presentations in …

Background. Emerging evidences suggest that in severe COVID-19, multi-organ failure is
associated with a hyperinflammatory state (the so-called “cytokine storm”) in combination …

Background Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic
state that places them at a dramatically increased lethal risk. Although platelet activation is …

In December 2019, a new and highly contagious infectious disease emerged in Wuhan,
China. The etiologic agent was identified as a novel coronavirus, now known as Severe …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a
global pandemic. In addition to the acute pulmonary symptoms of coronavirus disease …