Cytokines are secreted signalling proteins that play essential roles in the initiation,
maintenance and resolution of immune responses. Although the unique ability of cytokines …

Cytokines are secreted or membrane-presented molecules that mediate broad cellular
functions, including development, differentiation, growth and survival. Accordingly, the …

Cytokines exert a vast array of immunoregulatory actions critical to human biology and
disease. However, the desired immunotherapeutic effects of native cytokines are often …

Cytokines are immunoregulatory proteins involved in many pathological states with
promising potential as therapeutic agents. A diverse array of cytokines has been studied in …

Cytokines are secreted or otherwise released polypeptide factors that exert autocrine and/or
paracrine actions, with most cytokines acting in the immune and/or hematopoietic system …

Cytokines are small, secreted proteins associated with the maintenance of immune
homeostasis but also implicated with the pathogenesis of several autoimmune and …

Therapeutically controlling inflammation is essential for the clinical management of many
high-prevalence human diseases. Drugs that block the pro-inflammatory cytokines tumour …

Cytokines are critical mediators of communication for the immune system, and they are
essential for host defense against pathogens. Cytokines can be secreted by immune cells …

Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and
adaptive immune systems, mediating inflammation in response to a wide range of stimuli …

This review provides an historical account of the discovery and development of cytokines.
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular …