Pharmaceutical composition containing a stabilised mRNA optimised for translation in its coding regions
F Von Der Mülbe, I Hoerr, S Pascolo - US Patent 10,188,748, 2019 - Google Patents
The present invention relates to a pharmaceutical composi tion comprising a modified
mRNA that is stabilized by sequence modifications and optimized for translation. The …
mRNA that is stabilized by sequence modifications and optimized for translation. The …
PHARMACEUTICAL COMPOSITION CONTAINING A STABILISED mRNA OPTIMISED FOR TRANSLATION IN ITS CODING REGIONS
F Von Der Mûlbe, I Hoerr, S Pascolo - US Patent App. 13/185,119, 2011 - Google Patents
The present invention relates to a pharmaceutical composition comprising a modified mRNA
that is stabilized by sequence modifications and optimised for translation. The …
that is stabilized by sequence modifications and optimised for translation. The …
PHARMACEUTICAL COMPOSITION CONTAINING A STABILISED mRNA OPTIMISED FOR TRANSLATION IN ITS CODING REGIONS
F Von Der Mülbe, I Hoerr, S Pascolo - US Patent App. 12/787,755, 2010 - Google Patents
The present invention relates to a pharmaceutical composi tion containing an mRNA that is
stabilised by sequence modi fications in the translated region and is optimised for the …
stabilised by sequence modi fications in the translated region and is optimised for the …
Pharmaceutical composition containing a stabilised mrna optimised for translation in its coding regions
F Von Der Mülbe, I Hoerr, S Pascolo - US Patent App. 12/787,566, 2011 - Google Patents
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Modification of RNA, producing an increased transcript stability and translation efficiency
US9476055B2 - Modification of RNA, producing an increased transcript stability and translation
efficiency - Google Patents US9476055B2 - Modification of RNA, producing an increased …
efficiency - Google Patents US9476055B2 - Modification of RNA, producing an increased …
mRNA for use in treatment of human genetic diseases
BC Guild, M Heartlein - US Patent 8,853,377, 2014 - Google Patents
US8853377B2 - mRNA for use in treatment of human genetic diseases - Google Patents
US8853377B2 - mRNA for use in treatment of human genetic diseases - Google Patents mRNA …
US8853377B2 - mRNA for use in treatment of human genetic diseases - Google Patents mRNA …
mRNA for use in treatment of human genetic diseases
BC Guild, M Heartlein, F DeRosa - US Patent 9,061,021, 2015 - Google Patents
US9061021B2 - mRNA for use in treatment of human genetic diseases - Google Patents
US9061021B2 - mRNA for use in treatment of human genetic diseases - Google Patents mRNA …
US9061021B2 - mRNA for use in treatment of human genetic diseases - Google Patents mRNA …
RNA encoding a therapeutic protein
M Fotin-Mleczek, I Hoerr - US Patent 11,078,247, 2021 - Google Patents
The present invention relates to an RNA encoding a therapeutic protein. In particular, the
present invention relates to RNA suitable for use as a medicament. The present invention …
present invention relates to RNA suitable for use as a medicament. The present invention …
Modified RNA with decreased immunostimulatory properties
T Schlake, A Thess - US Patent 10,898,584, 2021 - Google Patents
9/1990 Mark et al. 11/1990 Caruthers et al. 5/1991 Lee et al. 9/1991 Andrus et al. 5/1992
Koths et al. 7/1992 Caruthers et al. 10/1992 Caruthers et al. 11/1993 Andrus et al. 12/1996 …
Koths et al. 7/1992 Caruthers et al. 10/1992 Caruthers et al. 11/1993 Andrus et al. 12/1996 …
Sense mrna therapy
K Wiederholt, T Woolf, M Taylor - US Patent App. 09/156,323, 2003 - Google Patents
The present invention describes novel methods for the stabilization of mRNA. These
alterations increase stability of mRNA and enable its use in sense RNA therapy to transiantly …
alterations increase stability of mRNA and enable its use in sense RNA therapy to transiantly …