Patients suffering from critical illness have host inflammatory responses against injuries,
such as infection and trauma, that can lead to tissue damage, organ failure, and death …

The gut is an important target organ for stress caused by severe insults such as sepsis,
trauma, burn, shock, bleeding and infection. Severe insult to the gut is considered to have an …

Critically ill patients have a hyper-inflammatory response against various offending injuries
that can result in tissue damage, organ failure, and fatal prognosis. The origin of this …

Critical illness results in significant changes in the human gut microbiota, leading to the
breakdown of the intestinal barrier function, which plays a role in the pathogenesis of …

Sepsis is the main cause of death in critically ill patients and gut microbiota dysbiosis plays a
crucial role in sepsis. On the one hand, sepsis leads to the destruction of gut microbiota and …

Sepsis is an overwhelming inflammatory response to microbial infection. Sepsis
management remains a clinical challenge. The role of the gut microbiome in sepsis has …

In health, a diverse microbiome might enhance host defense, while during critical illness, the
dysbiotic microbiome might contribute to comorbidity and organ dysfunction. Future research …

Clinicians have traditionally dichotomized bacteria as friendly commensals or harmful
pathogens. However, the line separating the two has become blurred with the recognition …

Background Microbial dysbiosis in critically ill patients is a leading cause of mortality and
septic complications. Probiotics and synbiotics have emerged as novel therapy on gut …

The gut microbiota plays a crucial role in the human microenvironment. Dysbiosis of the gut
microbiota is a common pathophysiological phenomenon in critically ill patients. Therefore …