An essential RNA-binding lysine residue in the Nab3 RRM domain undergoes mono and trimethylation

KY Lee, A Chopra, K Biggar, MD Meneghini - bioRxiv, 2019 - biorxiv.org
Abstract The Nrd1-Nab3-Sen1 (NNS) complex integrates molecular inputs to direct
termination of noncoding transcription in budding yeast. NNS is positively regulated by …

A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation

KY Lee, A Chopra, GL Burke, Z Chen… - Nucleic Acids …, 2020 - academic.oup.com
Abstract The Nrd1–Nab3–Sen1 (NNS) complex integrates molecular cues to direct
termination of noncoding transcription in budding yeast. NNS is positively regulated by …

[HTML][HTML] PAR-CLIP data indicate that Nrd1-Nab3-dependent transcription termination regulates expression of hundreds of protein coding genes in yeast

S Webb, RD Hector, G Kudla, S Granneman - Genome biology, 2014 - Springer
Abstract Background Nrd1 and Nab3 are essential sequence-specific yeast RNA binding
proteins that function as a heterodimer in the processing and degradation of diverse classes …

Yeast Nrd1, Nab3, and Sen1 transcriptome-wide binding maps suggest multiple roles in post-transcriptional RNA processing

N Jamonnak, TJ Creamer, MM Darby, P Schaughency… - Rna, 2011 - rnajournal.cshlp.org
RNA polymerase II transcribes both coding and noncoding genes, and termination of these
different classes of transcripts is facilitated by different sets of termination factors. Pre …

H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway

N Terzi, LS Churchman, L Vasiljeva… - … and cellular biology, 2011 - Taylor & Francis
In Saccharomyces cerevisiae, the Nrd1-Nab3-Sen1 pathway mediates the termination of
snoRNAs and cryptic unstable transcripts (CUTs). Both Nrd1 and the Set1 histone H3K4 …

[HTML][HTML] Mapping targets for small nucleolar RNAs in yeast

T Dudnakova, H Dunn-Davies, R Peters… - Wellcome open …, 2018 - ncbi.nlm.nih.gov
Background: Recent analyses implicate changes in the expression of the box C/D class of
small nucleolar RNAs (snoRNAs) in several human diseases. Methods: Here we report the …

[HTML][HTML] A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeast

N Leporé, DLJ Lafontaine - PLoS One, 2011 - journals.plos.org
Ribogenesis is a multistep error-prone process that is actively monitored by quality control
mechanisms. How ribosomal RNA synthesis, pre-rRNA processing and nucleolar …

[HTML][HTML] The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective

B Chaves-Arquero… - Biochemical Society …, 2023 - portlandpress.com
A substantial part of living cells activity involves transcription regulation. The RNA
polymerases responsible for this job need to know 'where/when'to start and stop in the …

Hijacking gene regulation in Saccharomyces cerevisae Utilization of the transcription terminating protein complex Nrd1-Nab3-Sen1

T Widén - 2019 - odr.chalmers.se
Sammanfattning The Nrd1-Nab3-Sen1 (NNS) complex in Saccharomyces cerevisiae is
essential for its role in terminating transcription for non-coding RNAs. However, it also …

H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway.

N Terzi Çizmecioğlu, L Vasiljeva, J Weissman… - 2011 - dspace.metu.edu.tr
In Saccharomyces cerevisiae, the Nrd1-Nab3-Sen1 pathway mediates the termination of
snoRNAs and cryptic unstable transcripts (CUTs). Both Nrd1 and the Set1 histone H3K4 …