Zearalenone as an endocrine disruptor in humans

K Kowalska, DE Habrowska-Górczyńska… - Environmental …, 2016 - Elsevier
Zearalenone (ZEA), a fungal mycotoxin, is present in a wide range of human foods. Many
animal studies have found ZEA to possess a disruptive effect on the hormonal balance …

Zearalenone and its metabolites as endocrine disrupting chemicals

M Metzler, E Pfeiffer… - World Mycotoxin …, 2010 - wageningenacademic.com
Zearalenone (ZEA) is a macrocyclic β-resorcylic acid lactone produced by numerous
species of Fusarium. It frequently contaminates corn and cereal products in many regions of …

Toxicity of zearalenone and its nutritional intervention by natural products

S Jing, C Liu, J Zheng, Z Dong, N Guo - Food & Function, 2022 - pubs.rsc.org
Zearalenone (ZEN) is a toxic secondary metabolite mainly produced by fungi of the genus
Fusarium, and is often present in various food and feed ingredients such as corn and wheat …

Zearalenone promotes cell proliferation or causes cell death?

W Zheng, B Wang, X Li, T Wang, H Zou, J Gu, Y Yuan… - Toxins, 2018 - mdpi.com
Zearalenone (ZEA), one of the mycotoxins, exerts different mechanisms of toxicity in different
cell types at different doses. It can not only stimulate cell proliferation but also inhibit cell …

Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassays

JM Molina-Molina, M Real, I Jimenez-Diaz… - Food and chemical …, 2014 - Elsevier
Zearalenone (ZEN) is a well-known mycotoxin present in numerous agricultural products.
Humans and animals are therefore at a risk of exposure to zearalenone through …

Effects of zearalenone and its derivatives on the synthesis and secretion of mammalian sex steroid hormones: A review

W Zheng, N Feng, Y Wang, L Noll, S Xu, X Liu… - Food and chemical …, 2019 - Elsevier
Abstract Zearalenone (ZEA), a non-steroidal estrogen mycotoxin produced by several
species of Fusarium fungi, can be metabolized into many other derivatives by …

Research progress of safety of zearalenone: A review

X Han, B Huangfu, T Xu, W Xu, C Asakiya, K Huang… - Toxins, 2022 - mdpi.com
Zearalenone, a mycotoxin produced by fungi of the genus Fusarium, widely exists in animal
feed and human food. The structure of zearalenone is similar to estrogen, so it mainly has …

Occurrence, impact on agriculture, human health, and management strategies of zearalenone in food and feed: A review

DK Mahato, S Devi, S Pandhi, B Sharma, KK Maurya… - Toxins, 2021 - mdpi.com
Mycotoxins represent an assorted range of secondary fungal metabolites that extensively
occur in numerous food and feed ingredients at any stage during pre-and post-harvest …

Gestational zearalenone exposure causes reproductive and developmental toxicity in pregnant rats and female offspring

X Gao, L Sun, N Zhang, C Li, J Zhang, Z Xiao, D Qi - Toxins, 2017 - mdpi.com
Zearalenone (ZEN) is an oestrogenic mycotoxin commonly found in food and feed products
and can affect reproduction and development in both humans and animals. This study …

Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin

A Zinedine, JM Soriano, JC Moltó, J Manes - Food and chemical toxicology, 2007 - Elsevier
Zearalenone (ZEA) is a mycotoxin produced mainly by fungi belonging to the genus
Fusarium in foods and feeds. It is frequently implicated in reproductive disorders of farm …