Marine sponges have been a prolific source of unique bioactive compounds that are
presumed to act as a deterrent to predation. Many of these compounds have potential …

Bacterial specialized metabolites are increasingly recognized as important factors in animal–
microbiome interactions: for example, by providing the host with chemical defenses. Even in …

There is increasing evidence that uncultivated bacterial symbionts are the true producers of
numerous bioactive compounds isolated from marine sponges. The localization and …

Marine sponge holobionts, defined as filter-feeding sponge hosts together with their
associated microbiomes, are prolific sources of natural products. The inventory of natural …

Marine sponges and their microbial symbiotic communities are rich sources of diverse
natural products (NPs) that often display biological activity, yet little is known about the …

Background Sponges are ancient sessile metazoans, which form with their associated
microbial symbionts a complex functional unit called a holobiont. Sponges are a rich source …

Sponges harbour complex communities of diverse microorganisms, which have been
postulated to form intimate symbiotic relationships with their host. Here we unravel some of …

Marine sponges are an unusually rich source of bioactive natural products with clinical
potential. They also often harbor rich communities of symbiotic bacteria that have often been …

Marine sponges are prolific sources of unique bioactive natural products. The sponge
Theonella swinhoei is represented by several distinct variants with largely nonoverlapping …

Sponges harbor a complex consortium of microbial communities living in symbiotic
relationship benefiting each other through the integration of metabolites. The mechanisms …