The maternal–fetal interface is an immunologically unique site that allows the tolerance to
the allogenic fetus and maintains host defense against possible pathogens. Balanced …

In pregnancy, successful implantation, placental development and fetal growth, as well as
maintenance of both maternal, and fetal health, requires balance of the immune response …

During pregnancy, the fetal-maternal interface underlies several dynamic alterations to
permit the fetus to be cultivated and developed in the uterus, in spite of being identifies by …

Fetomaternal immune tolerance is required to prevent fetal rejection during pregnancy;
simultaneously, the maternal immune system must also protect the fetus from harmful …

Although the mechanisms of immune-mediated pregnancy loss are unknown, investigations
are currently focused on mediators of immune activation and tissue injury at the maternal …

Simple Summary Pregnancy is a continually evolving process with many moving parts that
must be tightly regulated on both the maternal and fetal sides to ensure its success. A …

Recent research challenges long-held hypotheses about mechanisms through which
pregnancy induces maternal immune suppression or tolerance of the embryo/fetus. It is now …

Pregnancy is not as successful as one might think; it can be compromised by several
complications such as recurrent spontaneous miscarriage, pre-term delivery, pre-eclampsia …

Pregnancy stimulates an elaborate assortment of dynamic changes, allowing intimate
approximation of genetically discordant maternal and fetal tissues. Although the cellular and …

Maternal immune tolerance of the fetus is indispensable for a healthy pregnancy outcome.
Nowhere is this immune tolerance more important than at the fetal–maternal interface–the …