Nimesulide is a nonsteroidal anti-inflammatory drug possessing analgesic and antipyretic
properties. This drug is considered a selective cyclooxygenase-2 (COX-2) inhibitor and …

Cyclooxygenase-2 (COX-2) inhibitor nimesulide inhibits the proliferation of various types of
cancer cells mainly via COX-2 independent mechanisms, which makes it a good lead …

Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most prescribed
medications, although the chronic use of such pharmacological agents is commonly …

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a
cyclooxygenase-2 inhibitor but also has other novel pharmacological features which …

Nimesulide is a relatively selective cyclooxygenase (COX)-2 inhibitor, non-steroidal anti-
inflammatory drug; it has been discovered in 1971 and firstly commercialized in Italy in 1985 …

Nimesulide, a COX-2 selective drug, possesses anti-inflammatory and analgesic properties.
Moreover, it has low gastro-intestinal and renal toxicity. This paper presents industrially …

Seventeen new amide/sulfonamide containing nimesulide derivatives were synthesized and
characterized by several spectroscopic techniques and primarily investigated for their …

Nimesulide is a NSAID with good anti-inflammatory, analgesic and antipyretic activities
expected of such compounds. However, in addition it has some unique therapeutic and …

Non-steroidal anti-inflammatory drugs (NSAIDs), which are known to be cyclooxygenase
(COX) inhibitors, have been reported to exert anti-proliferative and pro-apoptotic effects on a …

Nimesulide, a COX-2 preferential inhibitor with a favorable gastric and cardiovascular safety
profile, was responsible for some cases of acute liver failure attributed to the nitrobenzene …