Today, articular cartilage damage is a major health problem, affecting people of all ages.
The existing conventional articular cartilage repair techniques, such as autologous …

Articular cartilage is a load‐bearing tissue playing a crucial mechanical role in diarthrodial
joints, facilitating joint articulation, and minimizing wear. The significance of biomechanical …

Defects in articular cartilage injury and chronic osteoarthritis are very widespread and
common, and the ability of injured cartilage to repair itself is limited. Stem cell-based …

Successful tissue regeneration therapies require further understanding of the environment in
which the cells are destined to be set. The aim is to structure approaches that aspire to a …

Mechanical factors play a crucial role in the development of articular cartilage in vivo. In this
regard, tissue engineers have sought to leverage native mechanotransduction pathways to …

In this review, we outline seminal and recent work highlighting the potential of mesenchymal
stem cells (MSCs) in producing cartilage-like tissue equivalents. Specific focus is placed on …

Chondrogenesis of dedifferentiated chondrocytes and mesenchymal stem cells is influenced
not only by soluble molecules like growth factors, but also by the cell environment itself. The …

Articular cartilage possesses little capacity for endogenous repair after having been
damaged by disease or trauma. Various surgical procedures depending on ingrowth of …

Abstract Background Mesenchymal stem cells (MSCs) hold promising translational potential
in cartilage regeneration. However, the efficacy of MSC-based tissue engineering is not …

Mesenchymal stem cells (MSCs) have the potential to replace or restore the function of
damaged tissues and offer much promise in the successful application of tissue engineering …