A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients

JS Allan, JE Coligan, TH Lee, MF McLane, PJ Kanki… - Science, 1985 - science.org
A newly identified protein from HTLV-III/LAV, the virus implicated as the etiologic agent of the
acquired immune deficiency syndrome, was studied. This protein, which has a molecular …

Binding of HTLV-III/LAV to T4+ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

JS McDougal, MS Kennedy, JM Sligh, SP Cort… - Science, 1986 - science.org
Human T-lymphotropic virus type III (HTLV-III) or lymphadenopathy-associated virus (LAV) is
tropic for human T cells with the helper-inducer phenotype, as defined by reactivity with …

Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients

F Barin, MF McLane, JS Allan, TH Lee, JE Groopman… - Science, 1985 - science.org
In this study, two glycoproteins (gp160 and gp120) that are encoded by human T-cell
lymphoma virus type III (HTLV-III) were the antigens most consistently recognized by …

Identification of HTLV-III/LAV sor Gene Product and Detection of Antibodies in Human Sera

NC Kan, G Franchini, F Wong-Staal, GC DuBois… - Science, 1986 - science.org
The nucleotide sequence of the genome of HTLV-III, the infectious agent etiologically
associated with the acquired immune deficiency syndrome, predicts a small open reading …

Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV

F di Marzo Veronese, TD Copeland, AL DeVico… - Science, 1986 - science.org
Approximately 80 percent of all human sera that react with antigens of HTLV-III, the etiologic
agent of the acquired immune deficiency syndrome (AIDS), recognize protein bands at 66 …

An HTLV-III peptide produced by recombinant DNA is immunoreactive with sera from patients with AIDS

NT Chang, J Huang, J Ghrayeb, S McKinney… - Nature, 1985 - nature.com
Human T-cell lymphotropic retrovirus type III (HTLV-III), also called lymphadenopathy-
associated virus (LAV), has been identified as the aetiological agent of acquired immune …

Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene

FDM Veronese, AL DeVico, TD Copeland, S Oroszlan… - Science, 1985 - science.org
Radiolabeled amino acid sequencing was used to characterize gp41, an antigen of HTLV-
III/LAV, the virus believed to be the etiological agent of the acquired immune deficiency …

HTLV-III in cells cultured from semen of two patients with AIDS

D Zagury, J Bernard, J Leibowitch, B Safai… - Science, 1984 - science.org
Epidemiological results suggest that the etiological agent of the acquired immune deficiency
syndrome (AIDS) is transmitted primarily through blood products, semen, and saliva. There …

Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS

MG Sarngadharan, M Popovic, L Bruch, J Schüpbach… - Science, 1984 - science.org
In cats, infection with T-lymphotropic retroviruses can cause T-cell proliferation and leukemia
or T-cell depletion and immunosuppression. In humans, some highly T4 tropic retroviruses …

Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III

JS Allan, JE Coligan, F Barin, MF McLane, JG Sodroski… - Science, 1985 - science.org
Antibodies from the serum of patients with the acquired immune deficiency syndrome (AIDS)
or with the AIDS-related complex and from the serum of seropositive healthy homosexuals …