The late endosomes/endo‐lysosomes of vertebrates contain an atypical phospholipid,
lysobisphosphatidic acid (LBPA)(also termed bis [monoacylglycero] phosphate [BMP]) …

We employed our recently developed immuno‐electron microscopic method (W. Möbius, Y.
Ohno‐Iwashita, EG van Donselaar, VM Oorschot, Y. Shimada, T. Fujimoto, HF Heijnen, HJ …

Lipids play an essential role in the structure of the endosomal membranes as well as in their
dynamic rearrangement during the transport of internalized cargoes along the endocytic …

Bis (monoacylglycero) phosphate (BMP) is a structural isomer of phosphatidylglycerol that
exhibits an unusual sn1: sn1′ stereoconfiguration, based on the position of the phosphate …

Abstract Bis (monoacylglycero) phosphate (BMP) is one of the most intriguing classes of
lipids discovered to date. Its biosynthetic pathway is still not fully known, even though studies …

Although understudied relative to many phospholipids, accumulating evidence suggests that
bis (monoacylglycero) phosphate (BMP) is an important class of regulatory lipid that plays …

Late endosomes accumulate internal membranes within the lumen of the organelle. These
internal membranes are enriched in the late endosome specific phospholipid …

Most cell types acquire cholesterol by endocytosis of circulating low density lipoprotein, but
little is known about the mechanisms of intra-endosomal cholesterol transport and about the …

The fate of free cholesterol released after endocytosis of low-density lipoproteins remains
obscure. Here we report that late endosomes have a pivotal role in intracellular cholesterol …

What do lysosomal storage disorders such as mucolipidosis type IV have in common with
Ebola, cancer cell migration, or LDL-cholesterol trafficking? LDL-cholesterol, certain …