Background Pancreatic cancer is one of the most lethal malignancies and has an extremely
poor diagnosis and prognosis. The development of resistance to gemcitabine is still a major …

Background Defective autophagy is thought to contribute to the pathogenesis of many
diseases, including cancer. Human plasmacytoma variant translocation 1 (PVT1) is an …

Objectives Elucidation of the regulatory mechanisms of gemcitabine sensitivity is needed to
improve the therapeutic effects of this drug in pancreatic cancer. Methods PANC-1 cells …

The identification and characterization of long non‐coding RNAs (lncRNAs) in diverse
biological process has currently developed rapidly. LncRNA‐PVT1, located adjacent to the …

Background: LncRNA PVT1 has been reported to be involved in a variety of biological
processes, including cell proliferation, cell differentiation and cancer progression. However …

Background The development of multidrug resistance (MDR) is a crucial problem of therapy
failure in gastric cancer, which results in disease recurrence and metastasis. Plasmacytoma …

Background The long non-coding RNA PVT1 (lncRNA PVT1) has been reported to act as an
oncogenic regulator of several cancers. However, its expression and function in gallbladder …

Pancreatic cancer is one of the most aggressive tumors associated with a poor clinical
prognosis, weakly effective therapeutic options. Therefore, there is a strong impetus to …

The pathogenesis and the underlying mechanisms of hepatocellular carcinoma (HCC)
remain unclear. LncRNA plasmacytoma variant translocation 1 (PVT1) is an oncogene in a …

Long noncoding RNAs (lncRNAs) have been reported to be involved in the occurrence and
tumorigenesis of numerous malignant cancers. Microarray expression profiles were used to …