Coumarins have attracted intense interest in recent years because they have been identified
from natural sources, especially green plants and have diverse pharmacological properties …

Quercetin is a plant-derived bioflavonoid that was recently shown to have multiple
anticancer activities in various solid tumors. Here, novel molecular mechanisms through …

Coumarin (1, 2-benzopyrone) is a naturally occurring fragrant compound found in a variety
of plants and spices. Coumarins have attracted intense interest in recent years because of …

Quercetin (a natural polyphenolic compound) is a polyphenolic flavonoid compound found
in a variety of plants. It has been demonstrated to exert cytostatic activity against a variety of …

Esculetin (6, 7-dihydroxycoumarin) is a coumarin derivative extracted from natural plants
and has been reported to have anticancer activity. However, the mechanism by which …

Several studies have shown that curcumin can induce apoptosis and inhibit growth in
human A549 lung adenocarcinoma cells. However, the mechanism is not completely …

Osteosarcoma is a mesenchymal malignant bone tumor accompanied by a high rate of lung
metastasis and short survival in dogs. Although various therapies have been reported, the …

Abstract The Akt/NF-κB pathways are involved in numerous anti-apoptotic and drug-
resistance events that occur in non‑small cell lung cancer (NSCLC). In the present study, the …

Curcumin (diferuloylmethane), an active component of the spice turmeric, induces apoptosis
in several types of malignancies. However, little is known about its anticancer activity in …

O-Geranylquercetin (GQ) is a novel O-alkylated derivate of quercetin. In this study, we
evaluated its apoptosis induction effects in human gastric cancer cell lines SGC-7901 and …