Background An increasing number of people survive cancer but a significant proportion
have gastrointestinal side effects as a result of radiotherapy (RT), which impairs their quality …

Background Across the developed world, an estimated 150,000 to 300,000 people are
treated annually with pelvic radiotherapy and 80% will develop gastrointestinal (GI) …

Background This is an update of a Cochrane review first published in 2002, and previously
updated in 2007. Late radiation rectal problems (proctopathy) include bleeding, pain, faecal …

Background A recent randomised trial suggested that an algorithmic approach to
investigating and managing gastrointestinal symptoms of pelvic radiation disease (PRD) is …

Background Chronic gastrointestinal symptoms after pelvic radiotherapy are common,
multifactorial in cause, and affect patients' quality of life. We assessed whether such patients …

Gastrointestinal toxicity after radiotherapy for pelvic cancer is a major complication—the
most commonly reported symptoms include rectal bleeding, diarrhea, and fecal …

Background. Cancer therapies increasingly achieve cure, but result in chronic moderate or
severe gastrointestinal side effects in millions of patients worldwide. Paradoxically, modern …

Up to 300 000 patients per year undergo pelvic radiotherapy worldwide. Nine out of 10 will
develop a permanent change in their bowel habit as a result. Five out of 10 of all patients will …

Purpose Although the multimodal cancer treatment techniques have greatly improved over
the years, irradiation-induced late gastrointestinal toxicity remains a great concern as it may …

Gastrointestinal symptoms after pelvic radiotherapy, which affect quality of life, are
substantially more common than generally recognised and are frequently poorly managed …