Insights from the first putative biosynthetic gene cluster for a lichen depside and depsidone
D Armaleo, X Sun, C Culberson - Mycologia, 2011 - Taylor & Francis
The genes for polyketide synthases (PKSs), enzymes that assemble the carbon backbones
of many secondary metabolites, often cluster with other secondary pathway genes. We …
of many secondary metabolites, often cluster with other secondary pathway genes. We …
Cloning and sequence characterization of a non-reducing polyketide synthase gene from the lichen Xanthoparmelia semiviridis
YH Chooi, DM Stalker, MA Davis, I Fujii, JA Elix… - Mycological …, 2008 - Elsevier
Lichens produce a diverse array of secondary metabolites that have shown various
biological activities. Of particular interest are the coupled phenolics that originate from …
biological activities. Of particular interest are the coupled phenolics that originate from …
Linking a gene cluster to atranorin, a major cortical substance of lichens, through genetic dereplication and heterologous expression
The depside and depsidone series compounds of polyketide origin accumulate in the
cortical or medullary layers of lichen thalli. Despite the taxonomic and ecological …
cortical or medullary layers of lichen thalli. Despite the taxonomic and ecological …
Characterization of a non-reducing polyketide synthase gene from lichen Dirinaria applanata
R Valarmathi, GN Hariharan, G Venkataraman… - Phytochemistry, 2009 - Elsevier
Lichens are known to produce a variety of secondary metabolites including polyketides that
have diverse biological role (s). The biosynthesis of fungal polyketides is governed by type I …
have diverse biological role (s). The biosynthesis of fungal polyketides is governed by type I …
Cloning and heterologous transcription of a polyketide synthase gene from the lichen Solorina crocea
AN Gagunashvili, SP Davíðsson, ZO Jónsson… - Mycological …, 2009 - Elsevier
Lichens and most ascomycete fungi produce polyketide secondary metabolites often with
valuable biological activities. Their biosynthesis is primarily governed by large iterative …
valuable biological activities. Their biosynthesis is primarily governed by large iterative …
[HTML][HTML] Identification of a lichen depside polyketide synthase gene by heterologous expression in Saccharomyces cerevisiae
JT Kealey, JP Craig, PJ Barr - Metabolic Engineering Communications, 2021 - Elsevier
Lichen-forming fungi produce a variety of secondary metabolites including bioactive
polyketides. Advances in DNA and RNA sequencing have led to a growing database of new …
polyketides. Advances in DNA and RNA sequencing have led to a growing database of new …
High Diversity of Type I Polyketide Genes in Bacidia rubella as Revealed by the Comparative Analysis of 23 Lichen Genomes
Fungi involved in lichen symbioses produce a large array of secondary metabolites that are
often diagnostic in the taxonomic delimitation of lichens. The most common lichen …
often diagnostic in the taxonomic delimitation of lichens. The most common lichen …
Lost in translation: challenges with heterologous expression of lichen polyketide synthases
RL Bertrand, JL Sorensen - ChemistrySelect, 2019 - Wiley Online Library
The ability to functionally express proteins in hosts is a precondition to an advanced
understanding of the biosynthetic pathways that are responsible for producing life's complex …
understanding of the biosynthetic pathways that are responsible for producing life's complex …
A transcribed polyketide synthase gene from Xanthoria elegans
G Brunauer, L Muggia, E Stocker-Wörgötter… - Mycological …, 2009 - Elsevier
We characterize the transcript of a polyketide synthase gene (PKS) from the cultured
mycobiont of Xanthoria elegans (XePKS1) using SMART-rapid amplification of cDNA ends …
mycobiont of Xanthoria elegans (XePKS1) using SMART-rapid amplification of cDNA ends …
Algal carbohydrates affect polyketide synthesis of the lichen-forming fungus Cladonia rangiferina
Lichen secondary metabolites (polyketides) are produced by the fungal partner, but the role
of algal carbohydrates in polyketide biosynthesis is not clear. This study examined whether …
of algal carbohydrates in polyketide biosynthesis is not clear. This study examined whether …