Parvalbumin (PV) interneurons are present in multiple brain regions and produce complex
influences on brain functioning. An increasing number of research findings indicate that the …

Abstract Parvalbumin-expressing (PV+) interneurons represent one of the most abundant
subclasses of cortical interneurons. Owing to their specific electrophysiological and synaptic …

The cognitive phenotype of autism has been correlated with an altered balance of excitation
to inhibition in the cerebral cortex, which could result from a change in the number, function …

Stress-related psychiatric disorders including depression involve complex cellular and
molecular changes in the brain, and GABAergic signaling dysfunction is increasingly …

Parvalbumin (PV) is a calcium binding protein expressed by inhibitory fast-spiking
interneurons in the cerebral cortex. By generating a fast stream of action potentials, PV+ …

Abstract Parvalbumin-expressing (PV+) inhibitory interneurons drive gamma oscillations (30–
80 Hz), which underlie higher cognitive functions. In this review, we discuss two …

The calcium binding protein parvalbumin (PV) in the mammalian neocortex is expressed in
a subpopulation of cortical GABAergic inhibitory interneurons. PV–producing interneurons …

Decreased GABAergic signaling is among the more robust pathologies observed
postmortem in schizophrenia; however, the functional consequences of this deficit are still …

Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique
morphological and functional properties that allow them to precisely control local circuitry …

Objective: Deficient excitatory drive to parvalbumin-containing cortical interneurons is
proposed as a key neural substrate for altered gamma oscillations and cognitive dysfunction …