Early detection and treatment of syphilis will reduce the infectious period and transmission.
We aimed to determine whether screening men who have sex with men (MSM) taking HIV …

Objectives We aimed to characterise patterns of anal and oral detection of Treponema
pallidum among men who have sex with men (MSM) with early syphilis. Methods 200 MSM …

Syphilis rates in much of the world are now at their highest levels in almost three decades,
and new approaches to controlling syphilis, including diagnostic tests with shorter window …

Background Syphilis is a growing public health problem among men who have sex with men
(MSM) globally. Rapid and accurate detection of syphilis is vital to ensure patients and their …

Background Syphilis transmission is increasing, and precisely how Treponema pallidum is
transmitted sexually from person to person is unclear. We aimed to determine the frequency …

Between 2010 and 2014, we obtained swab specimens to detect Treponema pallidum, with
PCR assays, from the oral cavities of 240 patients with 267 episodes of syphilis who …

Background Syphilis is a complex, multistage, sexually transmitted infection (STI) caused by
the bacterium Treponema pallidum subspecies pallidum (TP). New diagnostic tools are …

Background Syphilis diagnosis may be challenging, especially in the asymptomatic and
early clinical stages. We evaluated the presence of Treponema pallidum DNA (TP-DNA) in …

Background Serology is negative in a proportion of primary syphilis cases where
Treponema pallidum PCR testing is positive. We aimed to identify discordant, T. pallidum …

We investigated Treponema pallidum PCR positivity at mucosal sites (oral, anal, and vaginal
sites) among adults who had sexual contact with a person with syphilis (syphilis contacts) …