Objectives We evaluated a real-time quantitative PCR (qPCR) for detection of the
Treponema pallidum (TP) genome in clinical samples through simultaneous detection of two …

Background Early diagnosis of Treponema pallidum infection is helpful for disease
management, and conventional PCR is suitable for lesion swabs of patients with probable …

Syphilis, caused by Treponema pallidum subspecies pallidum (TP), is a complex multistage
infectious disease. Systematic dissemination occurs within a few hours of transmission. We …

Background Syphilis diagnosis may be challenging, especially in the asymptomatic and
early clinical stages. We evaluated the presence of Treponema pallidum DNA (TP-DNA) in …

The aim of this work was to investigate the application of the nested PCR assay for the
detection of Treponema pallidum (TP) DNA from the blood of patients with different stages of …

Background Syphilis is a complex, multistage, sexually transmitted infection (STI) caused by
the bacterium Treponema pallidum subspecies pallidum (TP). New diagnostic tools are …

Objectives: To investigate the contribution of a real-time PCR assay for the detection of
Treponema pallidum in various biological specimens with the secondary objective of …

Objectives Until recently, PCR had been used to detect but not quantify Treponema
pallidum. To understand infection kinetics of this uncultivable organism, a real-time PCR …

Syphilis, caused by Treponema pallidum ssp. pallidum (TPA), is a persisting global health
problem. Although syphilis diagnostics relies mainly on serology, serological tests have …

Background Syphilis is a sexually transmitted infection (STI) caused by the pathogen
Treponema pallidum. Its incidence is increasing in our country, especially among men who …